SCOPe 2.06: Domain d1gmna2: 1gmn A:126-207

Lineage for d1gmna2 (1gmn A:126-207)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.14: Kringle-like [57439] (1 superfamily)
   disulfide-rich fold; nearly all-beta

4. Superfamily g.14.1: Kringle-like [57440] (3 families)

5. Family g.14.1.1: Kringle modules [57441] (7 proteins)

6. Protein NK1 fragment of hepatocyte growth factor [57457] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57458] (18 PDB entries)

8. Domain d1gmna2: 1gmn A:126-207 [65316]
   Other proteins in same PDB: d1gmna1, d1gmnb1
   complexed with epe

Details for d1gmna2

PDB Entry: 1gmn, 2.3 Å

PDB Description: crystal structures of nk1-heparin complexes reveal the basis for nk1 activity and enable engineering of potent agonists of the met receptor

PDB Compounds: (A:) hepatocyte growth factor

SCOPe Domain Sequences for d1gmna2:

Sequence; same for both SEQRES and ATOM records:

>d1gmna2 g.14.1.1 (A:126-207) NK1 fragment of hepatocyte growth factor {Human (Homo sapiens) [TaxId: 9606]}
rnciigkgrsykgtvsitksgikcqpwssmiphehsflpssyrgkdlqenycrnprgeeg
gpwcftsnpevryevcdipqcs

Timeline for d1gmna2:

• d1gmna2 first appeared in SCOP 1.59
  
• d1gmna2 appears in SCOPe 2.05
  
• d1gmna2 appears in SCOPe 2.07
  
• d1gmna2 appears in the current release, SCOPe 2.08