SCOPe 2.02: Domain d1igwa_: 1igw A:

Lineage for d1igwa_ (1igw A:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families)

5. Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 proteins)
   forms a swapped dimer

6. Protein Isocitrate lyase [51642] (3 species)
   elaborated with additional subdomains

7. Species Escherichia coli [TaxId:562] [63923] (1 PDB entry)

8. Domain d1igwa_: 1igw A: [62370]
   complexed with hg, mg, pyr; mutant

Details for d1igwa_

PDB Entry: 1igw, 2.1 Å

PDB Description: crystal structure of the isocitrate lyase from the a219c mutant of escherichia coli

PDB Compounds: (A:) isocitrate lyase

SCOPe Domain Sequences for d1igwa_:

Sequence, based on SEQRES records:

>d1igwa_ c.1.12.7 (A:) Isocitrate lyase {Escherichia coli [TaxId: 562]}
ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges
kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv
erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa
avhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadli
tsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrf
aqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwfn
mfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqg

Sequence, based on observed residues (ATOM records):

>d1igwa_ c.1.12.7 (A:) Isocitrate lyase {Escherichia coli [TaxId: 562]}
ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges
kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv
erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa
avhfedqlasvkkcgkvlvptqeaiqklvaarlcadvtgvptllvartdadaadlitsdc
dpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrfaqai
hakypgkllayncsfqqqlsdmgykfqfitlagihsmwfnmfdlanayaqgegmkhyvek
vqqpefaaakdgytfvshqqevgtgyfdkvttiiqg

Timeline for d1igwa_:

• d1igwa_ first appeared in SCOP 1.57
  
• d1igwa_ appears in SCOPe 2.01
  
• d1igwa_ appears in SCOPe 2.03
  
• d1igwa_ appears in the current release, SCOPe 2.08