SCOP 1.65: Domain d1hjbf_: 1hjb F:

Lineage for d1hjbf_ (1hjb F:)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (8 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (6 families)

5. Family b.2.5.6: RUNT domain [81318] (1 protein)

6. Protein Acute myeloid leukemia 1 protein (AML1), RUNT domain [49439] (2 species)
   synonym: core binding factor alpha, cbfa

7. Species Mouse (Mus musculus) [TaxId:10090] [63684] (6 PDB entries)
   almost identical sequence to the human protein

8. Domain d1hjbf_: 1hjb F: [61078]
   Other proteins in same PDB: d1hjba_, d1hjbb_, d1hjbd_, d1hjbe_

Details for d1hjbf_

PDB Entry: 1hjb, 3 Å

PDB Description: crystal structure of runx-1/aml1/cbfalpha runt domain and c/ebpbeta bzip homodimer bound to a dna fragment from the csf-1r promoter

SCOP Domain Sequences for d1hjbf_:

Sequence; same for both SEQRES and ATOM records:

>d1hjbf_ b.2.5.6 (F:) Acute myeloid leukemia 1 protein (AML1), RUNT domain {Mouse (Mus musculus)}
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgpreprrh

Timeline for d1hjbf_:

• d1hjbf_ first appeared in SCOP 1.57
  
• d1hjbf_ appears in SCOP 1.63
  
• d1hjbf_ appears in SCOP 1.67
  
• d1hjbf_ appears in the current release, SCOPe 2.08