SCOPe 2.08: Family j.69.1.1: Tumor suppressor p53 fragments

Lineage for Family j.69.1.1: Tumor suppressor p53 fragments

1. Root: SCOPe 2.08

2. Class j: Peptides [58231] (151 folds)

3. Fold j.69: Tumor suppressor p53 fragments [58743] (1 superfamily)

4. Superfamily j.69.1: Tumor suppressor p53 fragments [58744] (1 family)

5. Family j.69.1.1: Tumor suppressor p53 fragments [58745] (2 proteins)

Proteins:

1. C-terminal negative regulatory domain [58746] (1 species)

   • Species Synthetic [58747] (1 PDB entry)

2. N-terminal, MDM-2 binding domain [103753] (1 species)
   selectively cytotoxic to cancer cells

   • Species Synthetic [103754] (2 PDB entries)

More info for Family j.69.1.1: Tumor suppressor p53 fragments

Timeline for Family j.69.1.1: Tumor suppressor p53 fragments:

• Family j.69.1.1: Tumor suppressor p53 fragments first appeared (with stable ids) in SCOP 1.55, called Family j.69.1.1: C-terminal negative regulatory domain of p53
  
• Family j.69.1.1: Tumor suppressor p53 fragments appears in SCOPe 2.07