SCOP 1.75: Family f.6.1.1: Leukocidin (pore-forming toxin)

Lineage for Family f.6.1.1: Leukocidin (pore-forming toxin)

1. Root: SCOP 1.75

2. Class f: Membrane and cell surface proteins and peptides [56835] (58 folds)

3. Fold f.6: Leukocidin-like [56958] (1 superfamily)
   subunit fold contains beta-sandwich of Ig-like (grerk-key) topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel

4. Superfamily f.6.1: Leukocidin-like [56959] (2 families)

5. Family f.6.1.1: Leukocidin (pore-forming toxin) [56960] (4 proteins)
   heptameric fold contains barrel (n=14, S=14) formed by beta-ribbon arms, one from each subunit

Proteins:

1. Alpha-hemolysin [56961] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [56962] (1 PDB entry)

2. Leucocidin K component LukF-PV [56963] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [56964] (1 PDB entry)

3. Leucocidin S component LukS-PV [111373] (1 species)

   • Species Staphylococcus aureus bacteriophage PVL [TaxId:71366] [111374] (1 PDB entry)
     Uniprot O80066

4. Leukocidin F (HlgB) [56965] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [56966] (3 PDB entries)

More info for Family f.6.1.1: Leukocidin (pore-forming toxin)

Timeline for Family f.6.1.1: Leukocidin (pore-forming toxin):

• Family f.6.1.1: Leukocidin (pore-forming toxin) first appeared (with stable ids) in SCOP 1.55
  
• Family f.6.1.1: Leukocidin (pore-forming toxin) appears in SCOP 1.73
  
• Family f.6.1.1: Leukocidin (pore-forming toxin) appears in SCOPe 2.01
  
• Family f.6.1.1: Leukocidin (pore-forming toxin) appears in the current release, SCOPe 2.08