SCOPe 2.08: Family f.6.1.1: Leukocidin (pore-forming toxin)

Lineage for Family f.6.1.1: Leukocidin (pore-forming toxin)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.6: Leukocidin-like [56958] (1 superfamily)
   subunit fold contains beta-sandwich of Ig-like (greek-key) topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel

4. Superfamily f.6.1: Leukocidin-like [56959] (3 families)

5. Family f.6.1.1: Leukocidin (pore-forming toxin) [56960] (5 proteins)
   heptameric fold contains barrel (n=14, S=14) formed by beta-ribbon arms, one from each subunit
   automatically mapped to Pfam PF07968

Proteins:

1. Alpha-hemolysin [56961] (2 species)

   1. Species Staphylococcus aureus [TaxId:1280] [56962] (9 PDB entries)

   2. Species Staphylococcus aureus [TaxId:548473] [259724] (1 PDB entry)

2. Leucocidin K component LukF-PV [56963] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [56964] (3 PDB entries)

3. Leucocidin S component LukS-PV [111373] (1 species)

   • Species Staphylococcus aureus bacteriophage PVL [TaxId:71366] [111374] (1 PDB entry)
     Uniprot O80066

4. Leukocidin F (HlgB) [56965] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [56966] (3 PDB entries)

5. automated matches [190904] (4 species)
   not a true protein

   1. Species Staphylococcus aureus [TaxId:1280] [382801] (1 PDB entry)

   2. Species Staphylococcus aureus [TaxId:158878] [189747] (5 PDB entries)

   3. Species Staphylococcus aureus [TaxId:196620] [188347] (1 PDB entry)

   4. Species Staphylococcus aureus [TaxId:282459] [257627] (2 PDB entries)

More info for Family f.6.1.1: Leukocidin (pore-forming toxin)

Timeline for Family f.6.1.1: Leukocidin (pore-forming toxin):

• Family f.6.1.1: Leukocidin (pore-forming toxin) first appeared (with stable ids) in SCOP 1.55
  
• Family f.6.1.1: Leukocidin (pore-forming toxin) appears in SCOPe 2.07