SCOPe 2.03: Protein: MAP kinase Erk2

Lineage for Protein: MAP kinase Erk2

Root: SCOPe 2.03
Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
members organized in the groups and subfamiles specified by the comments
Protein MAP kinase Erk2 [56134] (2 species)
CMGC group; ERK/MAPK subfamily; serine/threonine kinase

Species:

Human (Homo sapiens) [TaxId:9606] [56135] (1 PDB entry)
- Domain for 1pme:
  - Domain d1pmea_: 1pme A: [41653]
    complexed with sb2, so4; mutant
Norway rat (Rattus norvegicus) [TaxId:10116] [56136] (17 PDB entries)
1. Domain for 1erk:
  - Domain d1erka_: 1erk A: [41657]
2. Domain for 1gol:
  - Domain d1gola_: 1gol A: [41658]
    complexed with atp, mg; mutant
3. Domain for 2erk:
  - Domain d2erka_: 2erk A: [41655]
4. Domains for 2fys:
  1. Domain d2fysa_: 2fys A: [134389]
    automated match to d1erk__
  2. Domain d2fysb_: 2fys B: [134390]
    automated match to d1erk__
5. Domain for 2gph:
  - Domain d2gpha_: 2gph A: [164794]
    automated match to d1erka_
6. Domain for 2z7l:
  - Domain d2z7la_: 2z7l A: [154199]
    automated match to d1erka_
    complexed with bme, s91, so4
7. Domains for 3c9w:
  1. Domain d3c9wa_: 3c9w A: [156148]
    automated match to d2erka_
    complexed with hmy
  2. Domain d3c9wb_: 3c9w B: [156149]
    automated match to d2erka_
    complexed with hmy
8. Domain for 3erk:
  - Domain d3erka_: 3erk A: [41654]
    complexed with sb4
9. Domain for 3o71:
  - Domain d3o71a_: 3o71 A: [182850]
    automated match to d1erka_
    complexed with scn
10. Domain for 3qyi:
  - Domain d3qyia_: 3qyi A: [215491]
    automated match to d3erka_
    complexed with pg4, q23
11. Domain for 3qyw:
  - Domain d3qywa_: 3qyw A: [215495]
    automated match to d3erka_
    complexed with 6pb, dms, so4
12. Domain for 3qyz:
  - Domain d3qyza_: 3qyz A: [215496]
    automated match to d3erka_
    complexed with bme, dms, so4, z8b
13. Domain for 3r63:
  - Domain d3r63a_: 3r63 A: [193658]
    automated match to d1erka_
    mutant
14. Domain for 4erk:
  - Domain d4erka_: 4erk A: [41656]
    complexed with olo, so4
15. Domain for 4gsb:
  - Domain d4gsba_: 4gsb A: [194705]
    automated match to d1erka_
    complexed with gol, pge, so4
16. Domain for 4gt3:
  - Domain d4gt3a_: 4gt3 A: [194704]
    automated match to d1erka_
    complexed with atp, gol, mg, peg
17. Domain for 4gva:
  - Domain d4gvaa_: 4gva A: [194703]
    automated match to d1erka_
    complexed with adp, gol

More info for Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit:

Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit first appeared (with stable ids) in SCOP 1.55, called Protein MAP kinase Erk2 from d.144.1.1: Serine/threonin kinases
Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit appears in SCOPe 2.02
Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit appears in SCOPe 2.04
Protein MAP kinase Erk2 from d.144.1.7: Protein kinases, catalytic subunit appears in the current release, SCOPe 2.08