SCOPe 2.03: Domain d3c9wb_: 3c9w B:

Lineage for d3c9wb_ (3c9w B:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase Erk2 [56134] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [56136] (17 PDB entries)

8. Domain d3c9wb_: 3c9w B: [156149]
   automated match to d2erka_
   complexed with hmy

Details for d3c9wb_

PDB Entry: 3c9w, 2.5 Å

PDB Description: crystal structure of erk-2 with hypothemycin covalently bound

PDB Compounds: (B:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d3c9wb_:

Sequence, based on SEQRES records:

>d3c9wb_ d.144.1.7 (B:) MAP kinase Erk2 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
aagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgfltey
vatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsp
sqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqa
lahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqp

Sequence, based on observed residues (ATOM records):

>d3c9wb_ d.144.1.7 (B:) MAP kinase Erk2 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
aagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqr
tlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhic
yflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadptrwyrapeiml
nskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlka
rnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydps
depiaeapfkfdmelddlpkeklkelifeetarfqp

Timeline for d3c9wb_:

• d3c9wb_ first appeared in SCOP 1.75, called d3c9wb1
  
• d3c9wb_ appears in SCOPe 2.02
  
• d3c9wb_ appears in SCOPe 2.04
  
• d3c9wb_ appears in the current release, SCOPe 2.08, called d3c9wb2