Lineage for Family d.81.1.1: GAPDH-like

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
    core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1
  4. Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families) (S)
    N-terminal domain is the classic Rossmann-fold
  5. Family d.81.1.1: GAPDH-like [55348] (6 proteins)
    has many additional secondary structures

Proteins:

  1. Acetaldehyde dehydrogenase (acylating) [89988] (1 species)
  2. Aspartate beta-semialdehyde dehydrogenase [55361] (4 species)
    1. Species Escherichia coli [TaxId:562] [55362] (4 PDB entries)
      Uniprot P00353
    2. Species Haemophilus influenzae [TaxId:727] [103103] (12 PDB entries)
      Uniprot P44801
    3. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [143538] (18 PDB entries)
      Uniprot Q8DQ00 128-329
    4. Species Vibrio cholerae [TaxId:666] [82725] (4 PDB entries)
  3. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [55349] (21 species)
    1. Species Achromobacter xylosoxidans [TaxId:85698] [89987] (1 PDB entry)
      formerly Alcaligenes xylosoxidans
    2. Species American lobster (Homarus americanus) [TaxId:6706] [55358] (2 PDB entries)
    3. Species Bacillus stearothermophilus, nca 1503 [TaxId:1422] [55351] (11 PDB entries)
    4. Species Escherichia coli [TaxId:562] [55350] (12 PDB entries)
      Uniprot P06977
    5. Species Escherichia coli [TaxId:83333] [353049] (1 PDB entry)
    6. Species Escherichia coli [TaxId:83334] [336838] (1 PDB entry)
    7. Species Human (Homo sapiens) [TaxId:9606] [55360] (1 PDB entry)
    8. Species Human (Homo sapiens), liver isoform [TaxId:9606] [143535] (2 PDB entries)
      Uniprot P04406 151-314
    9. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [143536] (4 PDB entries)
      Uniprot Q8IKK7 153-318! Uniprot Q8T6B1 153-318
    10. Species Methanothermus fervidus [TaxId:2180] [55355] (1 PDB entry)
    11. Species Pyrococcus horikoshii [TaxId:53953] [143537] (1 PDB entry)
      Uniprot O59494 140-301
    12. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [103102] (1 PDB entry)
    13. Species South China Sea lobster (Palinurus versicolor) [TaxId:150436] [55359] (5 PDB entries)
    14. Species Spinach (Spinacia oleracea) [TaxId:3562] [69769] (8 PDB entries)
      Uniprot P19866
    15. Species Sulfolobus solfataricus [TaxId:2287] [55354] (1 PDB entry)
    16. Species Thermotoga maritima [TaxId:2336] [55353] (1 PDB entry)
    17. Species Thermus aquaticus [TaxId:271] [55352] (2 PDB entries)
    18. Species Thermus thermophilus [TaxId:274] [103101] (1 PDB entry)
    19. Species Trypanosoma brucei brucei, glycosome [TaxId:5702] [55356] (1 PDB entry)
    20. Species Trypanosoma cruzi [TaxId:5693] [75483] (5 PDB entries)
    21. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [55357] (5 PDB entries)
  4. N-acetyl-gamma-glutamyl-phosphate reductase ArgC [111046] (3 species)
    1. Species Salmonella typhimurium [TaxId:90371] [143539] (1 PDB entry)
      Uniprot Q8ZKL8 154-308
    2. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [118038] (2 PDB entries)
      Uniprot O82187 15-359
    3. Species Thermotoga maritima [TaxId:2336] [111047] (1 PDB entry)
      Uniprot Q9X2A2
  5. Putative semialdehyde dehydrogenase [143540] (1 species)
  6. Usg-1 protein homolog PA3116 [143542] (1 species)

More info for Family d.81.1.1: GAPDH-like

Timeline for Family d.81.1.1: GAPDH-like: