| Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
| Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily) consists of two intertwined (sub)domains related by pseudo dyad; duplication 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest |
Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) ![]() the constituent families form similar dimers |
| Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins) the active site is between the two identical subunits |
| Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (11 species) |
| Species Thermus thermophilus [TaxId:274] [53662] (14 PDB entries) |
| Domain d1dpza_: 1dpz A: [35053] |
| Domain d1dpzb_: 1dpz B: [35054] |
| Domain d1dr0a_: 1dr0 A: [35045] |
| Domain d1dr0b_: 1dr0 B: [35046] |
| Domain d1dr8a_: 1dr8 A: [35051] |
| Domain d1dr8b_: 1dr8 B: [35052] |
| Domain d1g2ua_: 1g2u A: [35036] mutant |
| Domain d1gc8a_: 1gc8 A: [35042] |
| Domain d1gc8b_: 1gc8 B: [35043] |
| Domain d1gc9a_: 1gc9 A: [35037] |
| Domain d1hexa_: 1hex A: [35044] complexed with nad |
| Domain d1idma_: 1idm A: [35035] |
| Domain d1ipda_: 1ipd A: [35038] complexed with so4 |
| Domain d1osia_: 1osi A: [35047] |
| Domain d1osib_: 1osi B: [35048] |
| Domain d1osic_: 1osi C: [35049] |
| Domain d1osid_: 1osi D: [35050] |
| Domain d1osja_: 1osj A: [35039] |
| Domain d1osjb_: 1osj B: [35040] |
| Domain d1wala_: 1wal A: [35041] mutant |
| Domain d1xaaa_: 1xaa A: [35033] |
| Domain d1xaba_: 1xab A: [35034] |
Timeline for Species Thermus thermophilus [TaxId:274] from c.77.1.1 3-isopropylmalate dehydrogenase, IPMDH: