SCOPe 2.02: Family c.69.1.2: Carboxylesterase

Lineage for Family c.69.1.2: Carboxylesterase

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.2: Carboxylesterase [53487] (7 proteins)

Proteins:

1. Carboxylesterase [53488] (3 species)
   bacterial homologue of human hormone sensitive lipase

   1. Species Alicyclobacillus acidocaldarius [TaxId:405212] [53490] (4 PDB entries)
      Uniprot Q7SIG1

   2. Species Archaeoglobus fulgidus [TaxId:2234] [69576] (1 PDB entry)

   3. Species Bacillus subtilis, brefeldin A esterase [TaxId:1423] [53489] (1 PDB entry)

2. Enterochelin esterase, catalytic domain [142699] (2 species)

   1. Species Shigella flexneri 2a str. 2457T [TaxId:198215] [159733] (3 PDB entries)

   2. Species Shigella flexneri [TaxId:623] [142700] (1 PDB entry)
      Uniprot Q83SB9 151-397

3. Feruloyl esterase domain of the cellulosomal xylanase y [69579] (1 species)

   • Species Clostridium thermocellum [TaxId:1515] [69580] (2 PDB entries)

4. Feruloyl esterase domain of the cellulosomal xylanase z [69577] (1 species)

   • Species Clostridium thermocellum [TaxId:1515] [69578] (2 PDB entries)

5. Heroin esterase [82493] (1 species)

   • Species Rhodococcus sp. [TaxId:1831] [82494] (2 PDB entries)

6. Uncharacterized protein TM1040_2492 [159734] (1 species)

   • Species Silicibacter sp. tm1040 [TaxId:292414] [159735] (1 PDB entry)
     Uniprot Q1GDP2 1-261

7. automated matches [190097] (2 species)
   not a true protein

   1. Species Clostridium thermocellum [TaxId:1094188] [193157] (1 PDB entry)

   2. Species Clostridium thermocellum [TaxId:1515] [186819] (3 PDB entries)

More info for Family c.69.1.2: Carboxylesterase

Timeline for Family c.69.1.2: Carboxylesterase:

• Family c.69.1.2: Carboxylesterase first appeared (with stable ids) in SCOP 1.55
  
• Family c.69.1.2: Carboxylesterase appears in SCOPe 2.01
  
• Family c.69.1.2: Carboxylesterase appears in SCOPe 2.03
  
• Family c.69.1.2: Carboxylesterase appears in the current release, SCOPe 2.08