Lineage for Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2875105Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2875106Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2875255Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4

Proteins:

  1. 2875256Protein-tyrosine phosphatase alpha [102420] (1 species)
  2. 2875260Protein-tyrosine phosphatase YopH, catalytic domain [100952] (2 species)
    1. 2875261Species Yersinia enterocolitica [TaxId:34055] [225588] (3 PDB entries)
    2. 2875265Species Yersinia enterocolitica [TaxId:630] [52812] (20 PDB entries)
  3. 2875290RPTP Lar [52815] (1 species)
    duplication: tandem repeat of the phosphatase domain
  4. 2875296SptP tyrosine phosphatase, catalytic domain [52813] (1 species)
  5. 2875300Tyrosine phosphatase [52806] (7 species)
    1. 2875301Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (264 PDB entries)
      Uniprot P18031 2-300 ! Uniprot P18031 1-298 ! Uniprot P18031 2-299
    2. 2875579Species Human (Homo sapiens), mu [TaxId:9606] [52808] (1 PDB entry)
      receptor protein tyrosine phosphatase mu, domain 1
    3. 2875582Species Human (Homo sapiens), shp-1 [TaxId:9606] [52811] (4 PDB entries)
    4. 2875587Species Human (Homo sapiens), shp-2 [TaxId:9606] [52810] (1 PDB entry)
    5. 2875590Species Human (Homo sapiens), T-cell [TaxId:9606] [75233] (1 PDB entry)
      non-receptor type 2
    6. 2875592Species Mouse (Mus musculus) [TaxId:10090] [52809] (1 PDB entry)
      receptor protein tyrosine phosphatase alpha, domain 1
    7. 2875595Species Mouse (Mus musculus), ptp-sl/br7 [TaxId:10090] [64051] (1 PDB entry)
  6. 2875597Tyrosine-protein phosphatase, non-receptor type 13 (PTPL1) [117581] (1 species)
  7. 2875600automated matches [190252] (5 species)
    not a true protein
    1. 2875601Species Avena sativa [TaxId:4498] [379243] (1 PDB entry)
    2. 2875603Species Human (Homo sapiens) [TaxId:9606] [187034] (47 PDB entries)
    3. 2875688Species Mouse (Mus musculus) [TaxId:10090] [233617] (1 PDB entry)
    4. 2875691Species Yersinia enterocolitica [TaxId:630] [226454] (1 PDB entry)
    5. 2875694Species Yersinia pestis [TaxId:632] [356707] (7 PDB entries)

More info for Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases

Timeline for Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases: