Lineage for Family c.8.2.1: LeuD-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2097883Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
    3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
    this domain is thought to be mobile in most multi-domain proteins known to contain it
  4. 2097920Superfamily c.8.2: LeuD/IlvD-like [52016] (4 families) (S)
    contains mixed beta-sheet barrel, closed n=7, S=10
  5. 2097921Family c.8.2.1: LeuD-like [52017] (4 protein domains)
    Pfam PF00694; permutation of the domain order in the proteins containing this family domain

Protein Domains:

  1. 2097922Aconitase A, C-terminal domain [52018] (2 species)
    other three domains have alpha/beta folds
    1. 2097923Species Cow (Bos taurus) [TaxId:9913] [52020] (9 PDB entries)
    2. 2097933Species Pig (Sus scrofa) [TaxId:9823] [52019] (6 PDB entries)
  2. 2097940Aconitase B, second N-terminal domain [75135] (1 species)
  3. 2097944Isopropylmalate isomerase LeuD [117454] (1 species)
    3-isopropylmalate dehydratase small subunit
  4. 2097948ron-responsive element binding protein 1, C-terminal domain [141974] (1 species)

More info for Family c.8.2.1: LeuD-like

Timeline for Family c.8.2.1: LeuD-like: