Lineage for Fold c.8: The 'swivelling' beta/beta/alpha domain

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2850950Fold c.8: The 'swivelling' beta/beta/alpha domain [52008] (10 superfamilies)
    3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
    this domain is thought to be mobile in most multi-domain proteins known to contain it

Superfamilies:

  1. 2850951c.8.1: Phosphohistidine domain [52009] (3 families) (S)
    contains barrel, closed, n=7, S=10
  2. 2850998c.8.2: LeuD/IlvD-like [52016] (4 families) (S)
    contains mixed beta-sheet barrel, closed n=7, S=10
  3. 2851056c.8.3: Carbamoyl phosphate synthetase, small subunit N-terminal domain [52021] (1 family) (S)
    automatically mapped to Pfam PF00988
  4. 2851100c.8.4: PA domain [52025] (1 family) (S)
  5. 2851157c.8.5: GroEL apical domain-like [52029] (3 families) (S)
  6. 2851416c.8.6: Swiveling domain of dehydratase reactivase alpha subunit [82317] (1 family) (S)
  7. 2851428c.8.7: RraA-like [89562] (2 families) (S)
    structural similarity and possible distant homology to the phosphohistidine domain of pyruvate phosphate dikinase
  8. 2851461c.8.8: Putative cyclase [102198] (2 families) (S)
    contains mixed beta-sheet barrel, closed n=7, S=10
  9. 2851495c.8.9: FumA C-terminal domain-like [117457] (1 family) (S)
    automatically mapped to Pfam PF05683
  10. 2851502c.8.10: LD-carboxypeptidase A C-terminal domain-like [141986] (1 family) (S)

More info for Fold c.8: The 'swivelling' beta/beta/alpha domain

Timeline for Fold c.8: The 'swivelling' beta/beta/alpha domain: