SCOPe 2.05: Superfamily c.8.2: LeuD/IlvD-like

Lineage for Superfamily c.8.2: LeuD/IlvD-like

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
   3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
   this domain is thought to be mobile in most multi-domain proteins known to contain it

4. Superfamily c.8.2: LeuD/IlvD-like [52016] (4 families)
   contains mixed beta-sheet barrel, closed n=7, S=10

Families:

1. c.8.2.1: LeuD-like [52017] (4 proteins)
   Pfam PF00694; permutation of the domain order in the proteins containing this family domain

2. c.8.2.2: IlvD/EDD C-terminal domain-like [141976] (1 protein)
   C-terminal part of Pfam PF00920

3. c.8.2.3: AF0055-like [141979] (1 protein)
   Pfam PF01989; DUF126; probable link between the LeuD-like and Phosphohistidine domain superfamilies (sequence similarity crosshits)

4. c.8.2.0: automated matches [191540] (1 protein)
   not a true family

More info for Superfamily c.8.2: LeuD/IlvD-like

Timeline for Superfamily c.8.2: LeuD/IlvD-like:

• Superfamily c.8.2: LeuD/IlvD-like first appeared (with stable ids) in SCOP 1.55, called Superfamily c.8.2: Aconitase, C-terminal domain
  
• Superfamily c.8.2: LeuD/IlvD-like appears in SCOPe 2.04
  
• Superfamily c.8.2: LeuD/IlvD-like appears in SCOPe 2.06
  
• Superfamily c.8.2: LeuD/IlvD-like appears in the current release, SCOPe 2.08