SCOPe 2.02: Protein: Short chain L-3-hydroxyacyl CoA dehydrogenase

Lineage for Protein: Short chain L-3-hydroxyacyl CoA dehydrogenase

Root: SCOPe 2.02
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (18 proteins)
the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
C-terminal domains also show some similarity

Protein Short chain L-3-hydroxyacyl CoA dehydrogenase [51874] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [51875] (11 PDB entries)
1. Domains for 1f0y:
  1. Domain d1f0ya2: 1f0y A:12-203 [30197]
    Other proteins in same PDB: d1f0ya1, d1f0yb1
    complexed with caa, nad
  2. Domain d1f0yb2: 1f0y B:12-203 [30198]
    Other proteins in same PDB: d1f0ya1, d1f0yb1
    complexed with caa, nad
2. Domains for 1f12:
  1. Domain d1f12a2: 1f12 A:12-203 [30207]
    Other proteins in same PDB: d1f12a1, d1f12b1
    complexed with 3hc
  2. Domain d1f12b2: 1f12 B:12-203 [30208]
    Other proteins in same PDB: d1f12a1, d1f12b1
    complexed with 3hc
3. Domains for 1f14:
  1. Domain d1f14a2: 1f14 A:12-203 [30205]
    Other proteins in same PDB: d1f14a1, d1f14b1
  2. Domain d1f14b2: 1f14 B:12-203 [30206]
    Other proteins in same PDB: d1f14a1, d1f14b1
4. Domains for 1f17:
  1. Domain d1f17a2: 1f17 A:12-203 [30201]
    Other proteins in same PDB: d1f17a1, d1f17b1
    complexed with nai
  2. Domain d1f17b2: 1f17 B:12-203 [30202]
    Other proteins in same PDB: d1f17a1, d1f17b1
    complexed with nai
5. Domains for 1il0:
  1. Domain d1il0a2: 1il0 A:12-203 [66190]
    Other proteins in same PDB: d1il0a1, d1il0b1
    complexed with caa, nad; mutant
  2. Domain d1il0b2: 1il0 B:12-203 [66192]
    Other proteins in same PDB: d1il0a1, d1il0b1
    complexed with caa, nad; mutant
6. Domains for 1lsj:
  1. Domain d1lsja2: 1lsj A:12-203 [91117]
    Other proteins in same PDB: d1lsja1, d1lsjb1
    complexed with nad; mutant
  2. Domain d1lsjb2: 1lsj B:12-203 [91119]
    Other proteins in same PDB: d1lsja1, d1lsjb1
    complexed with nad; mutant
7. Domains for 1lso:
  1. Domain d1lsoa2: 1lso A:12-203 [91121]
    Other proteins in same PDB: d1lsoa1, d1lsob1
    complexed with nad; mutant
  2. Domain d1lsob2: 1lso B:12-203 [91123]
    Other proteins in same PDB: d1lsoa1, d1lsob1
    complexed with nad; mutant
8. Domains for 1m75:
  1. Domain d1m75a2: 1m75 A:12-203 [91213]
    Other proteins in same PDB: d1m75a1, d1m75b1
    complexed with caa, nad; mutant
  2. Domain d1m75b2: 1m75 B:12-203 [91215]
    Other proteins in same PDB: d1m75a1, d1m75b1
    complexed with caa, nad; mutant
9. Domains for 1m76:
  1. Domain d1m76a2: 1m76 A:12-203 [91217]
    Other proteins in same PDB: d1m76a1, d1m76b1
    complexed with caa, nad; mutant
  2. Domain d1m76b2: 1m76 B:12-203 [91219]
    Other proteins in same PDB: d1m76a1, d1m76b1
    complexed with caa, nad; mutant
10. Domains for 2hdh:
  1. Domain d2hdha2: 2hdh A:12-203 [30199]
    Other proteins in same PDB: d2hdha1, d2hdhb1
    complexed with nad
  2. Domain d2hdhb2: 2hdh B:12-203 [30200]
    Other proteins in same PDB: d2hdha1, d2hdhb1
    complexed with nad
11. Domains for 3had:
  1. Domain d3hada2: 3had A:12-203 [30203]
    Other proteins in same PDB: d3hada1, d3hadb1
    complexed with nad
  2. Domain d3hadb2: 3had B:12-203 [30204]
    Other proteins in same PDB: d3hada1, d3hadb1
    complexed with nad
Pig (Sus scrofa) [TaxId:9823] [51876] (1 PDB entry)
- Domains for 3hdh:
  1. Domain d3hdha2: 3hdh A:12-203 [30209]
    Other proteins in same PDB: d3hdha1, d3hdhb1, d3hdhc1
    complexed with nad
  2. Domain d3hdhb2: 3hdh B:12-203 [30210]
    Other proteins in same PDB: d3hdha1, d3hdhb1, d3hdhc1
    complexed with nad
  3. Domain d3hdhc2: 3hdh C:12-203 [30211]
    Other proteins in same PDB: d3hdha1, d3hdhb1, d3hdhc1
    complexed with nad

More info for Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Timeline for Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain:

Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain first appeared (with stable ids) in SCOP 1.55
Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOPe 2.01
Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOPe 2.03
Protein Short chain L-3-hydroxyacyl CoA dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.08