SCOPe 2.01: Family c.1.11.2: D-glucarate dehydratase-like

Lineage for Family c.1.11.2: D-glucarate dehydratase-like

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.11: Enolase C-terminal domain-like [51604] (2 families)
   binds metal ion (magnesium or manganese) in conserved site inside barrel
   N-terminal alpha+beta domain is common to this superfamily

5. Family c.1.11.2: D-glucarate dehydratase-like [51609] (13 proteins)

Proteins:

1. beta-Methylaspartase [69400] (2 species)

   1. Species Citrobacter amalonaticus [TaxId:35703] [69402] (2 PDB entries)

   2. Species Clostridium tetanomorphum [TaxId:1553] [69401] (2 PDB entries)

2. Chlormuconate cycloisomerase [51619] (2 species)

   1. Species Alcaligenes eutrophus [TaxId:106590] [51620] (1 PDB entry)

   2. Species Pseudomonas sp. p51 [TaxId:65067] [102096] (1 PDB entry)

3. D-glucarate dehydratase [51610] (2 species)

   1. Species Escherichia coli [TaxId:562] [51612] (6 PDB entries)

   2. Species Pseudomonas putida [TaxId:303] [51611] (1 PDB entry)

4. Hypothetical protein Atu3453 [102097] (1 species)

   • Species Agrobacterium tumefaciens [TaxId:358] [102098] (1 PDB entry)

5. Hypothetical protein Bll6730 [117384] (1 species)

   • Species Bradyrhizobium japonicum [TaxId:375] [117385] (3 PDB entries)
     Uniprot Q89FH0

6. Hypothetical protein YitF [141844] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [141845] (2 PDB entries)
     Uniprot O06741 115-371

7. L-Ala-D/L-Glu epimerase [69397] (2 species)

   1. Species Bacillus subtilis [TaxId:1423] [69399] (2 PDB entries)
      Uniprot O34508

   2. Species Escherichia coli [TaxId:562] [69398] (1 PDB entry)

8. Mandelate racemase [51617] (1 species)

   • Species Pseudomonas putida [TaxId:303] [51618] (6 PDB entries)

9. Muconate-lactonizing enzyme [51615] (1 species)

   • Species Pseudomonas putida [TaxId:303] [51616] (5 PDB entries)

10. N-acylamino acid racemase [110372] (4 species)

    1. Species Amycolatopsis sp. [TaxId:37632] [110373] (4 PDB entries)
       Uniprot Q44244 # similar activity to a remotely related O-succinylbenzoate synthase from E. coli

    2. Species Deinococcus radiodurans [TaxId:1299] [110374] (4 PDB entries)
       Uniprot Q9RYA6

    3. Species Enterococcus faecalis [TaxId:1351] [117382] (1 PDB entry)
       Uniprot Q838J7; EF0450; protein assignment by sequence similarity

    4. Species Listeria innocua [TaxId:1642] [117383] (1 PDB entry)
       Uniprot Q927X3; Lin2664; protein assignment by sequence similarity

11. O-succinylbenzoate synthase [51613] (1 species)

    • Species Escherichia coli [TaxId:562] [51614] (4 PDB entries)

12. Putative dehydratase protein STM2273 [141846] (1 species)

    • Species Salmonella typhimurium [TaxId:90371] [141847] (1 PDB entry)
      Uniprot Q8ZNH1 123-400

13. RTS beta protein [117386] (1 species)

    • Species Xanthomonas campestris pv. campestris [TaxId:340] [117387] (1 PDB entry)
      Uniprot Q8P3K2; extended, mainly helical linker between the domains

More info for Family c.1.11.2: D-glucarate dehydratase-like

Timeline for Family c.1.11.2: D-glucarate dehydratase-like:

• Family c.1.11.2: D-glucarate dehydratase-like first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.11.2: D-glucarate dehydratase-like appears in SCOP 1.75
  
• Family c.1.11.2: D-glucarate dehydratase-like appears in SCOPe 2.02
  
• Family c.1.11.2: D-glucarate dehydratase-like appears in the current release, SCOPe 2.08