Lineage for Family c.1.2.1: Histidine biosynthesis enzymes

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 570217Fold c.1: TIM beta/alpha-barrel [51350] (32 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 570417Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (5 families) (S)
  5. 570418Family c.1.2.1: Histidine biosynthesis enzymes [51367] (2 proteins)
    structural evidence for the gene duplication within the barrel fold

Proteins:

  1. 570419Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF [51370] (4 species)
    1. 570420Species Archaeon Pyrobaculum aerophilum [TaxId:13773] [69380] (1 PDB entry)
    2. 570423Species Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId:4932] [69379] (4 PDB entries)
    3. 570432Species Thermotoga maritima [TaxId:243274] [51371] (3 PDB entries)
    4. 570438Species Thermus thermophilus [TaxId:274] [82237] (1 PDB entry)
  2. 570440Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368] (1 species)

More info for Family c.1.2.1: Histidine biosynthesis enzymes

Timeline for Family c.1.2.1: Histidine biosynthesis enzymes: