SCOPe 2.08: Family c.1.2.1: Histidine biosynthesis enzymes

Lineage for Family c.1.2.1: Histidine biosynthesis enzymes

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.1: Histidine biosynthesis enzymes [51367] (3 proteins)
   structural evidence for the gene duplication within the barrel fold
   automatically mapped to Pfam PF00977

Proteins:

1. Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF [51370] (4 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId:4932] [69379] (4 PDB entries)

   2. Species Pyrobaculum aerophilum [TaxId:13773] [69380] (1 PDB entry)

   3. Species Thermotoga maritima [TaxId:2336] [51371] (12 PDB entries)

   4. Species Thermus thermophilus [TaxId:274] [82237] (1 PDB entry)

2. Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368] (2 species)

   1. Species Streptomyces coelicolor [TaxId:1902] [141744] (1 PDB entry)
      Uniprot P16250 2-240

   2. Species Thermotoga maritima [TaxId:2336] [51369] (2 PDB entries)

3. automated matches [190186] (9 species)
   not a true protein

   1. Species Actinomyces urogenitalis [TaxId:525246] [269148] (1 PDB entry)

   2. Species Arthrobacter aurescens [TaxId:43663] [260126] (1 PDB entry)

   3. Species Corynebacterium efficiens [TaxId:152794] [226694] (1 PDB entry)

   4. Species Mycobacterium tuberculosis [TaxId:83332] [189657] (4 PDB entries)

   5. Species Streptomyces coelicolor [TaxId:100226] [277529] (1 PDB entry)

   6. Species Streptomyces coelicolor [TaxId:1902] [189237] (2 PDB entries)

   7. Species Streptomyces sp. [TaxId:465541] [259607] (2 PDB entries)

   8. Species Streptomyces sviceus [TaxId:463191] [258540] (2 PDB entries)

   9. Species Thermotoga maritima [TaxId:2336] [186925] (3 PDB entries)

More info for Family c.1.2.1: Histidine biosynthesis enzymes

Timeline for Family c.1.2.1: Histidine biosynthesis enzymes:

• Family c.1.2.1: Histidine biosynthesis enzymes first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.2.1: Histidine biosynthesis enzymes appears in SCOPe 2.07