Lineage for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2061576Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. 2061577Superfamily b.55.1: PH domain-like [50729] (14 families) (S)
  5. 2061849Family b.55.1.2: Phosphotyrosine-binding domain (PTB) [50755] (13 protein domains)
    Pfam PF00640

Protein Domains:

  1. 2061850Amyloid beta A4 precursor protein-binding family B member 2, Apbb2 [117259] (1 species)
  2. 2061854Disabled homolog 1 (Dab1) [89357] (1 species)
  3. 2061860Disabled homolog 2 (Dab2) [101830] (1 species)
  4. 2061868Docking protein 1, Dok1 [101834] (1 species)
  5. 2061874Downstream of tyrosine kinase 5, Dok-5 [101832] (1 species)
  6. 2061878EPS8-like protein 1, EPS8L1 [141424] (1 species)
  7. 2061881FGFR substrate 2 (SNT-1) [117257] (1 species)
  8. 2061884Insulin receptor substrate 1, IRS-1 [50758] (1 species)
    duplication: contains two domains of this fold
  9. 2061891Numb [50762] (2 species)
    1. 2061892Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [50763] (2 PDB entries)
    2. 2061895Species Mouse (Mus musculus) [TaxId:10090] [117256] (1 PDB entry)
      Uniprot Q9QZS3 19-172
  10. 2061897Shc adaptor protein [50760] (1 species)
  11. 2061902Tensin [141421] (2 species)
    1. 2061903Species Chicken (Gallus gallus) [TaxId:9031] [141423] (1 PDB entry)
      Uniprot Q04205 1606-1738
    2. 2061905Species Human (Homo sapiens) [TaxId:9606] [141422] (2 PDB entries)
      Uniprot Q9UPS7 1139-1285
      Tensin2
  12. 2061908X11 [50756] (1 species)
  13. 2061914automated matches [190580] (4 species)
    not a true protein
    1. 2061915Species Chicken (Gallus gallus) [TaxId:9031] [255189] (1 PDB entry)
    2. 2061917Species Human (Homo sapiens) [TaxId:9606] [188312] (4 PDB entries)
    3. 2061924Species Mouse (Mus musculus) [TaxId:10090] [187584] (1 PDB entry)
    4. 2061926Species Norway rat (Rattus norvegicus) [TaxId:10116] [226324] (1 PDB entry)

More info for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

Timeline for Family b.55.1.2: Phosphotyrosine-binding domain (PTB):