Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2061576Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. 2061577Superfamily b.55.1: PH domain-like [50729] (14 families) (S)
  5. 2061849Family b.55.1.2: Phosphotyrosine-binding domain (PTB) [50755] (13 protein domains)
    Pfam PF00640
  6. 2061884Protein Insulin receptor substrate 1, IRS-1 [50758] (1 species)
    duplication: contains two domains of this fold
  7. 2061885Species Human (Homo sapiens) [TaxId:9606] [50759] (2 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1irs:
    • 2061890Domain d1irsa_: 1irs A: [26991]
      second domain complexed with a IL-4 receptor phosphopeptide
  2. Domain(s) for 1qqg:
    1. 2061886Domain d1qqga1: 1qqg A:12-114 [26987]
    2. 2061887Domain d1qqga2: 1qqg A:159-262 [26988]
    3. 2061888Domain d1qqgb1: 1qqg B:11-114 [26989]
    4. 2061889Domain d1qqgb2: 1qqg B:159-264 [26990]

More info for Species Human (Homo sapiens) [TaxId:9606] from b.55.1.2 Insulin receptor substrate 1, IRS-1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.55.1.2 Insulin receptor substrate 1, IRS-1: