Lineage for Family b.34.2.1: SH3-domain

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2782725Fold b.34: SH3-like barrel [50036] (21 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. 2782861Superfamily b.34.2: SH3-domain [50044] (2 families) (S)
  5. 2782862Family b.34.2.1: SH3-domain [50045] (40 proteins)

Proteins:

  1. 278286353BP2 [50078] (1 species)
  2. 2782866Abl tyrosine kinase, SH3 domain [50052] (2 species)
    1. 2782867Species Human (Homo sapiens) [TaxId:9606] [50054] (6 PDB entries)
    2. 2782877Species Mouse (Mus musculus) [TaxId:10090] [50053] (3 PDB entries)
  3. 2782882Actin binding protein ABP1 [74920] (1 species)
  4. 2782886alpha-Spectrin, SH3 domain [50058] (1 species)
  5. 2782926Amphiphysin 2 [50080] (1 species)
    synonyms: Myc box dependent interacting protein 1, bin1
  6. 2782932BAI1-associated protein 2-like 1 (RIKEN cDNA 1300006m19) [110161] (1 species)
  7. 2782935Bruton's tyrosine kinase [50068] (1 species)
  8. 2782940BZZ1 [141188] (1 species)
  9. 2782943C-Crk, N-terminal SH3 domain [50046] (1 species)
  10. 2782953c-src protein tyrosine kinase [50064] (3 species)
    1. 2782954Species Avian sarcoma virus [TaxId:11876] [50067] (2 PDB entries)
      v-src
    2. 2782957Species Chicken (Gallus gallus) [TaxId:9031] [50066] (13 PDB entries)
    3. 2782975Species Human (Homo sapiens) [TaxId:9606] [50065] (7 PDB entries)
  11. 2782984Carboxyl-terminal src kinase (csk) [74654] (2 species)
    1. 2782985Species Human (Homo sapiens) [TaxId:9606] [74658] (2 PDB entries)
    2. 2782996Species Mouse (Mus musculus) [TaxId:10090] [74655] (1 PDB entry)
  12. 2782998EPS8 SH3 domain [50082] (1 species)
  13. 2783006Fyn proto-oncogene tyrosine kinase, SH3 domain [50048] (2 species)
    1. 2783007Species Chicken (Gallus gallus) [TaxId:9031] [256385] (2 PDB entries)
    2. 2783010Species Human (Homo sapiens) [TaxId:9606] [50049] (19 PDB entries)
  14. 2783036Fyn-binding protein (T-cell adapter protein adap) [101681] (1 species)
  15. 2783039Grb2-related adaptor protein 2 (Mona/Gads) [89293] (1 species)
  16. 2783045Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070] (3 species)
    1. 2783046Species Caenorhabditis elegans, SEM-5 [TaxId:6239] [50073] (5 PDB entries)
      Sex muscle abnormal protein 5
    2. 2783055Species Human (Homo sapiens) [TaxId:9606] [50071] (6 PDB entries)
    3. 2783066Species Mouse (Mus musculus) [TaxId:10090] [50072] (5 PDB entries)
  17. 2783072Hemapoetic cell kinase Hck [50062] (1 species)
  18. 2783122Hypothetical protein Baa76854.1 (KIAA1010) [101671] (1 species)
  19. 2783126Hypothetical protein YFR024c [101679] (1 species)
  20. 2783129IL-2 inducible T-cell (Itc) kinase [50060] (1 species)
  21. 2783132Intersectin 2 (KIAA1256) [101669] (1 species)
  22. 2783139Kalirin-9a [117147] (1 species)
  23. 2783142Melanoma inhibitory activity protein [63746] (1 species)
  24. 2783150Nck-2 [159019] (1 species)
  25. 2783154Olygophrenin-1 like protein (KIAA0621) [101673] (1 species)
  26. 2783157p47pox (neutrophil cytosolic factor 1) [89295] (1 species)
  27. 2783169p56-lck tyrosine kinase, SH3 domain [50076] (1 species)
  28. 2783181p67phox [74922] (1 species)
  29. 2783186Peroxisomal membrane protein Pex13p [82055] (1 species)
  30. 2783195Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055] (2 species)
    1. 2783196Species Cow (Bos taurus) [TaxId:9913] [50057] (2 PDB entries)
    2. 2783199Species Human (Homo sapiens) [TaxId:9606] [50056] (3 PDB entries)
  31. 2783203Phospholipase C, SH3 domain [50074] (1 species)
  32. 2783207Psd-95 [69248] (1 species)
    associates with a guanylate kinase domain
  33. 2783213Rac/CDC42 GEF 6 [101677] (1 species)
  34. 2783216RIM binding protein 2, RIMBP2 [117149] (1 species)
  35. 2783220SH3 domain from nebulin [50050] (1 species)
  36. 2783224SH3-like domain of the L-type calcium channel [110158] (2 species)
    1. 2783225Species Norway rat (Rattus norvegicus) [TaxId:10116] [110160] (5 PDB entries)
      Uniprot P54287 38-362
    2. 2783234Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110159] (5 PDB entries)
      Uniprot P54288
  37. 2783240Signal transducing adaptor molecule Stam2 [101675] (1 species)
  38. 2783243tyrosine kinase tec [69246] (1 species)
  39. 2783246Vav N-terminal SH3 domain [63744] (1 species)
  40. 2783254automated matches [190043] (8 species)
    not a true protein
    1. 2783255Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [186765] (4 PDB entries)
    2. 2783262Species Chicken (Gallus gallus) [TaxId:9031] [187080] (10 PDB entries)
    3. 2783277Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [255023] (4 PDB entries)
    4. 2783282Species Human (Homo sapiens) [TaxId:9606] [187799] (37 PDB entries)
    5. 2783335Species Mola mola [TaxId:94237] [386993] (1 PDB entry)
    6. 2783337Species Mouse (Mus musculus) [TaxId:10090] [187043] (7 PDB entries)
    7. 2783348Species Norway rat (Rattus norvegicus) [TaxId:10116] [187407] (7 PDB entries)
    8. 2783358Species Pig (Sus scrofa) [TaxId:9823] [391473] (1 PDB entry)

More info for Family b.34.2.1: SH3-domain

Timeline for Family b.34.2.1: SH3-domain: