Lineage for Family b.34.2.1: SH3-domain

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2045654Fold b.34: SH3-like barrel [50036] (21 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. 2045783Superfamily b.34.2: SH3-domain [50044] (2 families) (S)
  5. 2045784Family b.34.2.1: SH3-domain [50045] (40 protein domains)

Protein Domains:

  1. 204578553BP2 [50078] (1 species)
  2. 2045788Abl tyrosine kinase, SH3 domain [50052] (2 species)
    1. 2045789Species Human (Homo sapiens) [TaxId:9606] [50054] (6 PDB entries)
    2. 2045799Species Mouse (Mus musculus) [TaxId:10090] [50053] (3 PDB entries)
  3. 2045804Actin binding protein ABP1 [74920] (1 species)
  4. 2045808alpha-Spectrin, SH3 domain [50058] (1 species)
  5. 2045845Amphiphysin 2 [50080] (1 species)
    synonyms: Myc box dependent interacting protein 1, bin1
  6. 2045851BAI1-associated protein 2-like 1 (RIKEN cDNA 1300006m19) [110161] (1 species)
  7. 2045854Bruton's tyrosine kinase [50068] (1 species)
  8. 2045859BZZ1 [141188] (1 species)
  9. 2045862C-Crk, N-terminal SH3 domain [50046] (1 species)
  10. 2045872c-src protein tyrosine kinase [50064] (3 species)
    1. 2045873Species Avian sarcoma virus [TaxId:11876] [50067] (2 PDB entries)
      v-src
    2. 2045876Species Chicken (Gallus gallus) [TaxId:9031] [50066] (10 PDB entries)
    3. 2045887Species Human (Homo sapiens) [TaxId:9606] [50065] (6 PDB entries)
  11. 2045894Carboxyl-terminal src kinase (csk) [74654] (2 species)
    1. 2045895Species Human (Homo sapiens) [TaxId:9606] [74658] (2 PDB entries)
    2. 2045906Species Mouse (Mus musculus) [TaxId:10090] [74655] (1 PDB entry)
  12. 2045908EPS8 SH3 domain [50082] (1 species)
  13. 2045916Fyn proto-oncogene tyrosine kinase, SH3 domain [50048] (2 species)
    1. 2045917Species Chicken (Gallus gallus) [TaxId:9031] [256385] (2 PDB entries)
    2. 2045920Species Human (Homo sapiens) [TaxId:9606] [50049] (16 PDB entries)
  14. 2045943Fyn-binding protein (T-cell adapter protein adap) [101681] (1 species)
  15. 2045946Grb2-related adaptor protein 2 (Mona/Gads) [89293] (1 species)
  16. 2045952Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070] (3 species)
    1. 2045953Species Caenorhabditis elegans, SEM-5 [TaxId:6239] [50073] (5 PDB entries)
      Sex muscle abnormal protein 5
    2. 2045962Species Human (Homo sapiens) [TaxId:9606] [50071] (6 PDB entries)
    3. 2045973Species Mouse (Mus musculus) [TaxId:10090] [50072] (5 PDB entries)
  17. 2045979Hemapoetic cell kinase Hck [50062] (1 species)
  18. 2046022Hypothetical protein Baa76854.1 (KIAA1010) [101671] (1 species)
  19. 2046026Hypothetical protein YFR024c [101679] (1 species)
  20. 2046029IL-2 inducible T-cell (Itc) kinase [50060] (1 species)
  21. 2046032Intersectin 2 (KIAA1256) [101669] (1 species)
  22. 2046039Kalirin-9a [117147] (1 species)
  23. 2046042Melanoma inhibitory activity protein [63746] (1 species)
  24. 2046048Nck-2 [159019] (1 species)
  25. 2046052Olygophrenin-1 like protein (KIAA0621) [101673] (1 species)
  26. 2046055p47pox (neutrophil cytosolic factor 1) [89295] (1 species)
  27. 2046067p56-lck tyrosine kinase, SH3 domain [50076] (1 species)
  28. 2046079p67phox [74922] (1 species)
  29. 2046084Peroxisomal membrane protein Pex13p [82055] (1 species)
  30. 2046093Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055] (2 species)
    1. 2046094Species Cow (Bos taurus) [TaxId:9913] [50057] (2 PDB entries)
    2. 2046097Species Human (Homo sapiens) [TaxId:9606] [50056] (3 PDB entries)
  31. 2046101Phospholipase C, SH3 domain [50074] (1 species)
  32. 2046105Psd-95 [69248] (1 species)
    associates with a guanylate kinase domain
  33. 2046111Rac/CDC42 GEF 6 [101677] (1 species)
  34. 2046114RIM binding protein 2, RIMBP2 [117149] (1 species)
  35. 2046118SH3 domain from nebulin [50050] (1 species)
  36. 2046122SH3-like domain of the L-type calcium channel [110158] (2 species)
    1. 2046123Species Norway rat (Rattus norvegicus) [TaxId:10116] [110160] (5 PDB entries)
      Uniprot P54287 38-362
    2. 2046132Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110159] (4 PDB entries)
      Uniprot P54288
  37. 2046137Signal transducing adaptor molecule Stam2 [101675] (1 species)
  38. 2046140tyrosine kinase tec [69246] (1 species)
  39. 2046143Vav N-terminal SH3 domain [63744] (1 species)
  40. 2046151automated matches [190043] (6 species)
    not a true protein
    1. 2046152Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [186765] (4 PDB entries)
    2. 2046159Species Chicken (Gallus gallus) [TaxId:9031] [187080] (7 PDB entries)
    3. 2046170Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [255023] (4 PDB entries)
    4. 2046175Species Human (Homo sapiens) [TaxId:9606] [187799] (30 PDB entries)
    5. 2046205Species Mouse (Mus musculus) [TaxId:10090] [187043] (7 PDB entries)
    6. 2046216Species Norway rat (Rattus norvegicus) [TaxId:10116] [187407] (8 PDB entries)

More info for Family b.34.2.1: SH3-domain

Timeline for Family b.34.2.1: SH3-domain: