SCOPe 2.06: Family a.118.8.1: Tetratricopeptide repeat (TPR)

Lineage for Family a.118.8.1: Tetratricopeptide repeat (TPR)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.8: TPR-like [48452] (9 families)

5. Family a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (20 proteins)
   this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain

Proteins:

1. Bro1 [310760] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [311015] (1 PDB entry)

2. Cyclophilin 40 [63618] (1 species)

   • Species Cow (Bos taurus) [TaxId:9913] [63619] (2 PDB entries)

3. FKBP51, C-terminal domain [81905] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [81906] (1 PDB entry)

   2. Species Monkey (Saimiri boliviensis) [TaxId:27679] [81907] (1 PDB entry)

4. FKBP52 (FKBP4), C-terminal domain [109971] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [109972] (2 PDB entries)
     Uniprot Q02790 145-427

5. Hop [48456] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [48457] (4 PDB entries)

6. Hypothetical protein RSGI Ruh-001 [81908] (1 species)
   a Fis1p-like and Cgi-135 homologous domain

   • Species Mouse (Mus musculus) [TaxId:10090] [81909] (1 PDB entry)

7. Lipoprotein NlpI [117009] (2 species)

   1. Species Escherichia coli [TaxId:562] [117010] (1 PDB entry)
      Uniprot P39833 26-294

   2. Species Escherichia coli [TaxId:83333] [341925] (1 PDB entry)

8. Menin C-terminal domain [310725] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [310974] (23 PDB entries)

   2. Species Nematostella vectensis [TaxId:45351] [310973] (1 PDB entry)

9. Mitochondria fission protein Fis1 [101417] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [140836] (3 PDB entries)
      Uniprot P40515 1-138

   2. Species Human (Homo sapiens) [TaxId:9606] [101418] (2 PDB entries)

10. Mitochondrial import receptor subunit tom20-3 [140839] (1 species)

    • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [140840] (1 PDB entry)
      Uniprot P82874 1-145

11. Neutrophil cytosolic factor 2 (NCF-2, p67-phox) [48460] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [48461] (2 PDB entries)

12. O-GlcNAc transferase, OGT [109973] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [109974] (1 PDB entry)
       Uniprot O15294 16-400

    2. Species Xanthomonas campestris [TaxId:314565] [254861] (1 PDB entry)

13. Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) [48462] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [48463] (1 PDB entry)

    2. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [63617] (6 PDB entries)

14. Prolyl 4-hydroxylase alpha-1 subunit, P4HA1 [117007] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [117008] (1 PDB entry)
      Uniprot P13674 161-254

15. Protein phosphatase 5 [48454] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [48455] (3 PDB entries)

16. Putative 70 kda peptidylprolyl isomerase PFL2275c [140841] (1 species)

    • Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [140842] (1 PDB entry)
      Uniprot Q8I4V8 128-280

17. SMG-7 [140843] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [140844] (1 PDB entry)
      Uniprot Q92540 1-497

18. STIP1 homology and U box-containing protein 1, STUB1 [140837] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [140838] (1 PDB entry)
      Uniprot Q9WUD1 24-224

19. Vesicular transport protein sec17 [48458] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [48459] (1 PDB entry)

20. automated matches [190103] (4 species)
    not a true protein

    1. Species Bacillus subtilis [TaxId:1423] [161323] (1 PDB entry)

    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [226182] (1 PDB entry)

    3. Species Human (Homo sapiens) [TaxId:9606] [186825] (11 PDB entries)

    4. Species Yersinia enterocolitica [TaxId:630] [161324] (1 PDB entry)

More info for Family a.118.8.1: Tetratricopeptide repeat (TPR)

Timeline for Family a.118.8.1: Tetratricopeptide repeat (TPR):

• Family a.118.8.1: Tetratricopeptide repeat (TPR) first appeared (with stable ids) in SCOP 1.55
  
• Family a.118.8.1: Tetratricopeptide repeat (TPR) appears in SCOPe 2.05
  
• Family a.118.8.1: Tetratricopeptide repeat (TPR) appears in SCOPe 2.07
  
• Family a.118.8.1: Tetratricopeptide repeat (TPR) appears in the current release, SCOPe 2.08