![]() | Class a: All alpha proteins [46456] (290 folds) |
![]() | Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily) multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry |
![]() | Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families) ![]() N-terminal domain is Rossmann-fold with a family-specific C-terminal extension |
![]() | Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) [48184] (3 proteins) |
![]() | Class I ketol-acid reductoisomerase [89101] (1 species) |
![]() | Species Pseudomonas aeruginosa [TaxId:287] [89102] (1 PDB entry) |
![]() | Class II ketol-acid reductoisomerase [48185] (1 species) duplication; contains two structural repeats swapped to fold into a figure eight knot |
![]() | Species Spinach (Spinacia oleracea) [TaxId:3562] [48186] (2 PDB entries) |
![]() | automated matches [227000] (2 species) not a true protein |
![]() | Species Azotobacter vinelandii [TaxId:322710] [271797] (1 PDB entry) |
![]() | Species Oryza sativa [TaxId:39947] [225644] (2 PDB entries) |
Timeline for Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI):