Lineage for Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2329494Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  4. 2329495Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families) (S)
    N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
  5. 2329529Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI) [48184] (3 protein domains)

Protein Domains:

  1. 2329530Class I ketol-acid reductoisomerase [89101] (1 species)
  2. 2329536Class II ketol-acid reductoisomerase [48185] (1 species)
    duplication; contains two structural repeats swapped to fold into a figure eight knot
  3. 2329546automated matches [227000] (2 species)
    not a true protein
    1. 2329547Species Azotobacter vinelandii [TaxId:322710] [271797] (1 PDB entry)
    2. 2329552Species Oryza sativa [TaxId:39947] [225644] (2 PDB entries)

More info for Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)

Timeline for Family a.100.1.2: Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI):