SCOPe 2.01: Family a.39.1.2: S100 proteins

Lineage for Family a.39.1.2: S100 proteins

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.2: S100 proteins [47478] (2 proteins)
   dimer: subunits are made of two EF-hands

Proteins:

1. Calcyclin (S100) [47479] (17 species)

   1. Species Cow (Bos taurus), s100b [TaxId:9913] [47482] (14 PDB entries)

   2. Species Human (Homo sapiens), calgranulin C, s100a12 [TaxId:9606] [47488] (3 PDB entries)

   3. Species Human (Homo sapiens), calgranulin s100a8, MRP8 [TaxId:9606] [47487] (2 PDB entries)
      Migration inhibitory factor-related protein 8

   4. Species Human (Homo sapiens), P11 s100a10, calpactin [TaxId:9606] [47484] (2 PDB entries)
      ligand of annexin II

   5. Species Human (Homo sapiens), psoriasin s100a7 [TaxId:9606] [47485] (3 PDB entries)

   6. Species Human (Homo sapiens), s100a13 [TaxId:9606] [140535] (4 PDB entries)
      Uniprot Q99584 1-98

   7. Species Human (Homo sapiens), s100a3 [TaxId:9606] [74720] (1 PDB entry)

   8. Species Human (Homo sapiens), s100a4 [TaxId:9606] [81754] (5 PDB entries)
      MTS1 protein

   9. Species Human (Homo sapiens), s100a6 [TaxId:9606] [74719] (4 PDB entries)

   10. Species Human (Homo sapiens), s100a9 (mrp14) [TaxId:9606] [69020] (2 PDB entries)

   11. Species Human (Homo sapiens), s100b [TaxId:9606] [47483] (6 PDB entries)

   12. Species Human (Homo sapiens), s100p [TaxId:9606] [81755] (2 PDB entries)

   13. Species Pig (Sus scrofa), calgizzarin s100c (s100a11) [TaxId:9823] [47486] (1 PDB entry)

   14. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47480] (5 PDB entries)

   15. Species Rabbit (Oryctolagus cuniculus), calgizzarin s100a11 [TaxId:9986] [89047] (1 PDB entry)

   16. Species Rat (Rattus norvegicus), s100a1 [TaxId:10116] [69019] (3 PDB entries)

   17. Species Rat (Rattus norvegicus), s100b [TaxId:10116] [47481] (6 PDB entries)

2. automated matches [190132] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [187203] (16 PDB entries)

   2. Species Zebrafish (Danio rerio) [TaxId:7955] [189706] (1 PDB entry)

More info for Family a.39.1.2: S100 proteins

Timeline for Family a.39.1.2: S100 proteins:

• Family a.39.1.2: S100 proteins first appeared (with stable ids) in SCOP 1.55
  
• Family a.39.1.2: S100 proteins appears in SCOP 1.75
  
• Family a.39.1.2: S100 proteins appears in SCOPe 2.02
  
• Family a.39.1.2: S100 proteins appears in the current release, SCOPe 2.08