Lineage for Family a.39.1.2: S100 proteins

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1994319Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 1994320Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 1994353Family a.39.1.2: S100 proteins [47478] (2 protein domains)
    dimer: subunits are made of two EF-hands

Protein Domains:

  1. 1994354Calcyclin (S100) [47479] (17 species)
    1. 1994355Species Cow (Bos taurus), s100b [TaxId:9913] [47482] (26 PDB entries)
    2. 1994390Species Human (Homo sapiens), calgranulin C, s100a12 [TaxId:9606] [47488] (3 PDB entries)
    3. 1994411Species Human (Homo sapiens), calgranulin s100a8, MRP8 [TaxId:9606] [47487] (5 PDB entries)
      Migration inhibitory factor-related protein 8
    4. 1994429Species Human (Homo sapiens), P11 s100a10, calpactin [TaxId:9606] [47484] (2 PDB entries)
      ligand of annexin II
    5. 1994434Species Human (Homo sapiens), psoriasin s100a7 [TaxId:9606] [47485] (3 PDB entries)
    6. 1994440Species Human (Homo sapiens), s100a13 [TaxId:9606] [140535] (2 PDB entries)
      Uniprot Q99584 1-98
    7. 1994444Species Human (Homo sapiens), s100a3 [TaxId:9606] [74720] (1 PDB entry)
    8. 1994447Species Human (Homo sapiens), s100a4 [TaxId:9606] [81754] (9 PDB entries)
      MTS1 protein
    9. 1994492Species Human (Homo sapiens), s100a6 [TaxId:9606] [74719] (4 PDB entries)
    10. Species Human (Homo sapiens), s100a9 (mrp14) [TaxId:9606] [69020] (1 PDB entry)
    11. 1994507Species Human (Homo sapiens), s100b [TaxId:9606] [47483] (11 PDB entries)
    12. 1994529Species Human (Homo sapiens), s100p [TaxId:9606] [81755] (2 PDB entries)
    13. 1994533Species Norway rat (Rattus norvegicus), s100a1 [TaxId:10116] [69019] (4 PDB entries)
    14. 1994542Species Norway rat (Rattus norvegicus), s100b [TaxId:10116] [47481] (7 PDB entries)
    15. 1994557Species Pig (Sus scrofa), calgizzarin s100c (s100a11) [TaxId:9823] [47486] (1 PDB entry)
    16. 1994559Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47480] (5 PDB entries)
    17. 1994570Species Rabbit (Oryctolagus cuniculus), calgizzarin s100a11 [TaxId:9986] [89047] (1 PDB entry)
  2. 1994573automated matches [190132] (4 species)
    not a true protein
    1. 1994574Species Cow (Bos taurus) [TaxId:9913] [193459] (1 PDB entry)
    2. 1994576Species Human (Homo sapiens) [TaxId:9606] [187203] (42 PDB entries)
    3. 1994669Species Mouse (Mus musculus) [TaxId:10090] [269737] (1 PDB entry)
    4. 1994671Species Zebrafish (Danio rerio) [TaxId:7955] [189706] (1 PDB entry)

More info for Family a.39.1.2: S100 proteins

Timeline for Family a.39.1.2: S100 proteins: