SCOPe 2.08: Family a.21.1.1: HMG-box

Lineage for Family a.21.1.1: HMG-box

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.21: HMG-box [47094] (1 superfamily)
   3 helices; irregular array

4. Superfamily a.21.1: HMG-box [47095] (2 families)

5. Family a.21.1.1: HMG-box [47096] (10 proteins)

Proteins:

1. High mobility group protein 1, HMG1 [47097] (2 species)
   duplication: contains HMG-box domains

   1. Species Chinese hamster (Cricetulus griseus) [TaxId:10029] [47099] (5 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [47098] (4 PDB entries)

2. High mobility group protein 2, HMG2 [109762] (1 species)

   • Species Pig (Sus scrofa) [TaxId:9823] [109763] (3 PDB entries)
     Uniprot P17741 1-77, 89-163

3. HMG-D [47100] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [47101] (3 PDB entries)

4. Lymphoid enhancer-binding factor, LEF1 [47110] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [47111] (1 PDB entry)

5. NHP6a [47102] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47103] (3 PDB entries)

6. Nucleolar transcription factor 1 (Upstream binding factor 1, UBF-1) [68982] (2 species)
   Contains 6 HMG-box domains

   1. Species Human (Homo sapiens) [TaxId:9606] [68983] (3 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [109764] (3 PDB entries)
      Uniprot P25976 388-383, 392-470, 567-655

7. Sox-2 [81718] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [101105] (3 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [81719] (1 PDB entry)

8. Sox-5 [47106] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [47107] (1 PDB entry)

9. SRY [47104] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47105] (5 PDB entries)

10. automated matches [190434] (3 species)
    not a true protein

    1. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [189474] (2 PDB entries)

    2. Species Human (Homo sapiens) [TaxId:9606] [187328] (5 PDB entries)

    3. Species Mouse (Mus musculus) [TaxId:10090] [188832] (3 PDB entries)

More info for Family a.21.1.1: HMG-box

Timeline for Family a.21.1.1: HMG-box:

• Family a.21.1.1: HMG-box first appeared (with stable ids) in SCOP 1.55
  
• Family a.21.1.1: HMG-box appears in SCOPe 2.07