SCOPe 2.05: Family a.4.5.21: ets domain

Lineage for Family a.4.5.21: ets domain

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (85 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.21: ets domain [46859] (9 proteins)

Proteins:

1. E74-like factor 5 ese-2b [140269] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140270] (1 PDB entry)
     Uniprot Q9UKW6 173-265

2. Elk-1 [46871] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [46872] (1 PDB entry)

3. ETS-1 transcription factor, residues 331-440 [46862] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [46864] (3 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [46863] (6 PDB entries)
      Uniprot P27577 301-440

4. Fli-1 [46860] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [46861] (1 PDB entry)

5. GA binding protein (GABP) alpha [46867] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [46868] (1 PDB entry)

6. Sam pointed domain containing ets transcription SPDEF [140267] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140268] (1 PDB entry)
     Uniprot O95238 247-334

7. Serum response factor accessory protein 1a, SAP-1 [46869] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [46870] (4 PDB entries)

8. Transcription factor PU.1, residues 171-259 [46865] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [46866] (1 PDB entry)

9. automated matches [191121] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [193283] (12 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [189188] (1 PDB entry)

More info for Family a.4.5.21: ets domain

Timeline for Family a.4.5.21: ets domain:

• Family a.4.5.21: ets domain first appeared (with stable ids) in SCOP 1.55
  
• Family a.4.5.21: ets domain appears in SCOPe 2.04
  
• Family a.4.5.21: ets domain appears in SCOPe 2.06
  
• Family a.4.5.21: ets domain appears in the current release, SCOPe 2.08