SCOP 1.69: Domain d1tgk__: 1tgk -

Lineage for d1tgk__ (1tgk -)

1. Root: SCOP 1.69

2. Class g: Small proteins [56992] (75 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (7 proteins)

6. Protein TGF-beta3 [57508] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57509] (3 PDB entries)

8. Domain d1tgk__: 1tgk - [44776]

Details for d1tgk__

PDB Entry: 1tgk, 3.3 Å

PDB Description: human transforming growth factor beta 3, crystallized from peg 4000

SCOP Domain Sequences for d1tgk__:

Sequence; same for both SEQRES and ATOM records:

>d1tgk__ g.17.1.2 (-) TGF-beta3 {Human (Homo sapiens)}
aldtnycfrnleenccvrplyidfrqdlgwkwvhepkgyyanfcsgpcpylrsadtthst
vlglyntlnpeasaspccvpqdlepltilyyvgrtpkveqlsnmvvksckcs

Timeline for d1tgk__:

• d1tgk__ first appeared (with stable ids) in SCOP 1.55
  
• d1tgk__ appears in SCOP 1.67
  
• d1tgk__ appears in SCOP 1.71
  
• d1tgk__ appears in the current release, SCOPe 2.08, called d1tgka_