SCOP 1.67: Domain d1cmwa4: 1cmw A:423-832

Lineage for d1cmwa4 (1cmw A:423-832)

1. Root: SCOP 1.67

2. Class e: Multi-domain proteins (alpha and beta) [56572] (40 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (3 proteins)

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Thermus aquaticus [TaxId:271] [56676] (13 PDB entries)

8. Domain d1cmwa4: 1cmw A:423-832 [42994]
   Other proteins in same PDB: d1cmwa1, d1cmwa2, d1cmwa3

Details for d1cmwa4

PDB Entry: 1cmw, 2.6 Å

PDB Description: crystal structure of taq dna-polymerase shows a new orientation for the structure-specific nuclease domain

SCOP Domain Sequences for d1cmwa4:

Sequence, based on SEQRES records:

>d1cmwa4 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraa
ktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvet
lfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllq
vhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake

Sequence, based on observed residues (ATOM records):

>d1cmwa4 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus}
eerllwlyreverplsavlahmeatgvrldvaylralslevaleaevfrlaghpfnlnsr
dqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklkstyid
plpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaeegwllv
aldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraaktinf
gvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvetlfgrr
ryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllqvhdel
vleapkeraeavarlakevmegvyplavplevevgigedwlsake

Timeline for d1cmwa4:

• d1cmwa4 first appeared (with stable ids) in SCOP 1.55
  
• d1cmwa4 appears in SCOP 1.65
  
• d1cmwa4 appears in SCOP 1.69
  
• d1cmwa4 last appears in SCOP 1.75