Lineage for d7jxlc_ (7jxl C:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2981114Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2981115Species Human (Homo sapiens) [TaxId:9606] [82796] (133 PDB entries)
    Uniprot P00533 702-1018
  8. 3086605Domain d7jxlc_: 7jxl C: [422922]
    automated match to d3ikaa_
    complexed with vo7

Details for d7jxlc_

PDB Entry: 7jxl (more details), 2.4 Å

PDB Description: egfr kinase (t790m/v948r) in complex with az5104
PDB Compounds: (C:) Epidermal growth factor receptor

SCOPe Domain Sequences for d7jxlc_:

Sequence, based on SEQRES records: (download)

>d7jxlc_ d.144.1.7 (C:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
nqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankei
ldeayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqyllnwcv
qiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpik
wmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppic
tidvymimrkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyr
almdeedm

Sequence, based on observed residues (ATOM records): (download)

>d7jxlc_ d.144.1.7 (C:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
nqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelrespkankeild
eayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqyllnwcvqi
akgmnyledrrlvhrdlaarnvlvktpqhvkitdfglaklvpikwmalesilhriythqs
dvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimrkcwmida
dsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyralmdeedm

SCOPe Domain Coordinates for d7jxlc_:

Click to download the PDB-style file with coordinates for d7jxlc_.
(The format of our PDB-style files is described here.)

Timeline for d7jxlc_:

  • d7jxlc_ is new in SCOPe 2.08-stable