SCOP 1.65: Domain d1a36a2: 1a36 A:431-633,A:713-765

Lineage for d1a36a2 (1a36 A:431-633,A:713-765)

1. Root: SCOP 1.65

2. Class d: Alpha and beta proteins (a+b) [53931] (234 folds)

3. Fold d.163: DNA breaking-rejoining enzymes [56348] (1 superfamily)
   core: alpha3-beta3-alpha4; one side of beta-sheet is exposed

4. Superfamily d.163.1: DNA breaking-rejoining enzymes [56349] (2 families)

5. Family d.163.1.2: Eukaryotic DNA topoisomerase I, catalytic core [56361] (1 protein)

6. Protein Eukaryotic DNA topoisomerase I, catalytic core [56362] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56363] (8 PDB entries)

8. Domain d1a36a2: 1a36 A:431-633,A:713-765 [42173]
   Other proteins in same PDB: d1a36a1, d1a36a3
   protein/DNA complex; mutant

Details for d1a36a2

PDB Entry: 1a36, 2.8 Å

PDB Description: topoisomerase i/dna complex

SCOP Domain Sequences for d1a36a2:

Sequence; same for both SEQRES and ATOM records:

>d1a36a2 d.163.1.2 (A:431-633,A:713-765) Eukaryotic DNA topoisomerase I, catalytic core {Human (Homo sapiens)}
pssrikgekdwqkyetarrlkkcvdkirnqyredwkskemkvrqravalyfidklalrag
nekeegetadtvgccslrvehinlhpeldgqeyvvefdflgkdsiryynkvpvekrvfkn
lqlfmenkqpeddlfdrlntgilnkhlqdlmegltakvfrtynasitlqqqlkeltapde
nipakilsynranravailcnhqXqialgtsklnfldpritvawckkwgvpiekiynktq
rekfawaidmadedyef

Timeline for d1a36a2:

• d1a36a2 first appeared (with stable ids) in SCOP 1.55
  
• d1a36a2 appears in SCOP 1.63
  
• d1a36a2 appears in SCOP 1.67
  
• d1a36a2 appears in the current release, SCOPe 2.08