SCOPe 2.02: Domain d1d5fb_: 1d5f B:

Lineage for d1d5fb_ (1d5f B:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (1 family)

5. Family d.148.1.1: Hect, E3 ligase catalytic domain [56205] (2 proteins)

6. Protein Ubiquitin-protein ligase E3a (E6ap) [56206] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56207] (2 PDB entries)

8. Domain d1d5fb_: 1d5f B: [41770]

Details for d1d5fb_

PDB Entry: 1d5f, 2.8 Å

PDB Description: structure of e6ap: insights into ubiquitination pathway

PDB Compounds: (B:) e6ap hect catalytic domain, e3 ligase

SCOPe Domain Sequences for d1d5fb_:

Sequence; same for both SEQRES and ATOM records:

>d1d5fb_ d.148.1.1 (B:) Ubiquitin-protein ligase E3a (E6ap) {Human (Homo sapiens) [TaxId: 9606]}
npylrlkvrrdhiiddalvrlemiamenpadlkkqlyvefegeqgvdeggvskeffqlvv
eeifnpdigmftydestklfwfnpssfetegqftligivlglaiynncildvhfpmvvyr
klmgkkgtfrdlgdshpvlyqslkdlleyegnveddmmitfqisqtdlfgnpmmydlken
gdkipitnenrkefvnlysdyilnksvekqfkafrrgfhmvtnesplkylfrpeeielli
cgsrnldfqaleetteydggytrdsvlirefweivhsftdeqkrlflqfttgtdrapvgg
lgklkmiiakngpdterlptshtcfnvlllpeysskeklkerllkaitya

Timeline for d1d5fb_:

• d1d5fb_ first appeared (with stable ids) in SCOP 1.55
  
• d1d5fb_ appears in SCOPe 2.01
  
• d1d5fb_ appears in SCOPe 2.03
  
• d1d5fb_ appears in the current release, SCOPe 2.08