SCOPe 2.08: Domain d6nnab3: 6nna B:1877-2113

Lineage for d6nnab3 (6nna B:1877-2113)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (319 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186944] (65 PDB entries)

8. Domain d6nnab3: 6nna B:1877-2113 [416399]
   Other proteins in same PDB: d6nnaa1, d6nnab1
   automated match to d2vz8ac
   complexed with edo, kua, ndp

Details for d6nnab3

PDB Entry: 6nna, 2.26 Å

PDB Description: human fatty acid synthase psi/kr tri-domain with nadph and compound 22

PDB Compounds: (B:) Fatty acid synthase,Fatty acid synthase

SCOPe Domain Sequences for d6nnab3:

Sequence, based on SEQRES records:

>d6nnab3 c.2.1.0 (B:1877-2113) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sktfcpahksyiiagglggfglelaqwliqrgvqklvltsrsgirtgyqakqvrrwrrqg
vqvqvstsnisslegargliaeaaqlgpvggvfnlavvlrdgllenqtpeffqdvckpky
sgtlnldrvtreacpeldyfvvfssvscgrgnagqsnygfansamericekrrheglpgl
avqwgaigdvgilvetmstndtivsgtlpqrmasclevldlflnqphmvlssfvlae

Sequence, based on observed residues (ATOM records):

>d6nnab3 c.2.1.0 (B:1877-2113) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sktfcpahksyiiagglggfglelaqwliqrgvqklvltsrsgirtgyqakqvrrwrrqg
vqvqvstsnisslegargliaeaaqlgpvggvfnlavvlrdgllenqtpeffqdvckpky
sgtlnldrvtreacpeldyfvvfssvscgrgnagqsnygfansamericekrrheglpgl
avqwgaigdvgilvetdtivsgtlpqrmasclevldlflnqphmvlssfvlae

Timeline for d6nnab3:

• d6nnab3 is new in SCOPe 2.08-stable