SCOPe 2.08: Domain d7mtuh1: 7mtu H:1-486

Lineage for d7mtuh1 (7mtu H:1-486)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (16 species)
   not a true protein

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [330485] (6 PDB entries)

8. Domain d7mtuh1: 7mtu H:1-486 [405750]
   Other proteins in same PDB: d7mtua2, d7mtub2, d7mtuc2, d7mtud2, d7mtue2, d7mtuf2, d7mtug2, d7mtuh2
   automated match to d5uwxb_
   complexed with edo, gol, imp, k, zo7

Details for d7mtuh1

PDB Entry: 7mtu, 2.34 Å

PDB Description: crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from bacillus anthracis in the complex with imp and the inhibitor p221

PDB Compounds: (H:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d7mtuh1:

Sequence, based on SEQRES records:

>d7mtuh1 c.1.5.0 (H:1-486) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvteadma
iamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasvda
ivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpgsi
cttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgsmf
agvaespgeteiyqgrqfkvyrgmgsvgamekgskdryfqegnkklvpegiegrvpykgp
ladtvhqlvgglragmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapnys

Sequence, based on observed residues (ATOM records):

>d7mtuh1 c.1.5.0 (H:1-486) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvteadma
iamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasvda
ivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpgsi
cttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgsmf
agvaespgeteiyqgrqfkvyrgmgsvgameklvpegiegrvpykgpladtvhqlvgglr
agmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapnys

Timeline for d7mtuh1:

• d7mtuh1 first appeared in SCOPe 2.07