SCOPe 2.07: Domain d6vpfb_: 6vpf B:

Lineage for d6vpfb_ (6vpf B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d6vpfb_: 6vpf B: [392774]
   automated match to d3erta_
   complexed with 53q

Details for d6vpfb_

PDB Entry: 6vpf, 1.6 Å

PDB Description: estrogen receptor alpha ligand binding domain in complex with the selective estrogen receptor modulator clomiphene

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d6vpfb_:

Sequence, based on SEQRES records:

>d6vpfb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld
ahrl

Sequence, based on observed residues (ATOM records):

>d6vpfb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkknvvpsydlllemlda
hrl

Timeline for d6vpfb_:

• d6vpfb_ is new in SCOPe 2.07-stable
  
• d6vpfb_ appears in the current release, SCOPe 2.08