SCOPe 2.08: Domain d6vfda_: 6vfd A:

Lineage for d6vfda_ (6vfd A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)

6. Protein Trp synthase alpha-subunit [51388] (9 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (72 PDB entries)

8. Domain d6vfda_: 6vfd A: [392632]
   Other proteins in same PDB: d6vfdb_
   automated match to d1k8ya_
   complexed with 1d0, cl, cs, dms, edo, ser; mutant

Details for d6vfda_

PDB Entry: 6vfd, 1.7 Å

PDB Description: tryptophan synthase mutant q114a in complex with cesium ion at the metal coordination site and 2-aminophenol quinonoid at the enzyme beta site

PDB Compounds: (A:) tryptophan synthase alpha chain

SCOPe Domain Sequences for d6vfda_:

Sequence, based on SEQRES records:

>d6vfda_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra

Sequence, based on observed residues (ATOM records):

>d6vfda_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytylllhh
lieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspkqmlael
rsfvsamkaasra

Timeline for d6vfda_:

• d6vfda_ first appeared in SCOPe 2.07