PDB entry 6vfd

View 6vfd on RCSB PDB site
Description: Tryptophan synthase mutant Q114A in complex with cesium ion at the metal coordination site and 2-aminophenol quinonoid at the enzyme beta site
Class: lyase
Keywords: protein complex, LYASE
Deposited on 2020-01-03, released 2020-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tryptophan synthase alpha chain
    Species: Salmonella typhimurium [TaxId:90371]
    Gene: trpA, DD95_04145
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6vfda_
  • Chain 'B':
    Compound: tryptophan synthase beta chain
    Species: Salmonella typhimurium [TaxId:90371]
    Gene: trpB, AAP89_02045, ABO94_19170, AF480_03975, AF488_06015, AF489_02660, AIC76_02215, AU613_22485, AXR84_21850, AXU58_18720, C2253_17845, CD48_01255, CE87_00490, CET98_00490, CQG18_02715, CVR97_02985, D4369_03495, D4380_02480, D4401_03780, D4E62_00155, D6360_05135, D7F20_01770, D7H43_22440, DD95_04150, DJ388_09100, DKJ11_03255, DKU57_01740, DLM31_00170, DNV30_02640, DO698_02865, DOJ90_01720, DOQ88_05395, DQ848_22185, DRM14_00170, DSF69_00170, DSR36_00155, DUW48_00170, E2F01_02625, EBO41_01950, EBP31_03920, EGU67_04975, EHB24_02705, EHC98_05585, EIW53_01745, F0A00_14785, F0A01_15745, F0A02_08960, F0A03_20195, F0A04_22070, F0A05_01740, F0A06_01905, F0A07_12870, F0A08_01425, F0U66_12100, FKA80_16460, FKA81_16995, FKA82_17080, FKA83_17705, FKA84_18900, FKA85_16755, FKA86_15095, FKA87_20420, FKA88_00465, FKA89_17495, FKA90_04050, FKA91_03380, FKA92_00475, FKA93_04425, FKA94_02440, FKA95_00475, FKA96_03185, FKA97_05420, FKA98_04655, FKA99_00465, FKB00_08210, FKB01_00475, FKB02_00470, FKB03_06095, FKB12_08200, FKB15_09545, FKB19_17260, FYL57_17810, FYL66_01025, FYL68_08225, FYL69_04355, FYL71_20365, FYL73_06975, FYL74_10415, FYL75_12085, FYL77_17200, FYL81_18315, FYL84_11395, FYL90_05690, FYL92_04810, FYL93_03130, FYL94_11585, FYL96_18520, FYM06_17485, FYM08_08630, FYM09_19335, FYM12_03600, FYM54_08665, FZ992_19115, FZ993_02220, FZ994_08290, FZ995_12310, FZ996_09230, FZ997_15170, FZ998_14625, FZ999_17455, GW08_03175, JO10_00490, LZ63_02660, NG18_14010, NU83_02660, QA89_14465, QB40_00170, QD15_05225, RJ78_16500, SAMEA4398682_02247, UPM260_1493, Y934_00965, YG50_13195, YI33_00155, YR17_00170, YT65_03520, ZA53_18735, ZB89_05455, ZC54_00170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6vfdb_
  • Heterogens: 1D0, EDO, SER, DMS, CL, CS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vfdA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra

    Sequence, based on observed residues (ATOM records): (download) 
    >6vfdA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytylllhh
lieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspkqmlael
rsfvsamkaasra

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6vfdB (B:)
mttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptalt
kcqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagahgvasa
lasallglkcriymgakdverqspnvfrmrlmgaevipvhsgsatlkdacnealrdwsgs
yetahymlgtaagphpyptivrefqrmigeetkaqildkegrlpdaviacvgggsnaigm
fadfindtsvgligvepgghgietgehgaplkhgrvgiyfgmkapmmqtadgqieesysi
sagldfpsvgpqhaylnsigradyvsitddealeafktlcrhegiipalesshalahalk
mmreqpekeqllvvnlsgrgdkdiftvhdilkargei

    Sequence, based on observed residues (ATOM records): (download) 
    >6vfdB (B:)
ttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptaltk
cqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagahgvasal
asallglkcriymgakdverqspnvfrmrlmgaevipvhsgsatlkdacnealrdwsgsy
etahymlgtaagphpyptivrefqrmigeetkaqildkegrlpdaviacvgggsnaigmf
adfindtsvgligvepgghgietgehgaplkhgrvgiyfgmkapmmqtadgqieesysis
agldfpsvgpqhaylnsigradyvsitddealeafktlcrhegiipalesshalahalkm
mreqpekeqllvvnlsgrgdkdiftvhdilkarge