SCOPe 2.08: Domain d6uifa_: 6uif A:

Lineage for d6uifa_ (6uif A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.69: 7-bladed beta-propeller [50964] (15 superfamilies)
   consists of seven 4-stranded beta-sheet motifs; meander

4. Superfamily b.69.4: WD40 repeat-like [50978] (4 families)
   also contains 8-bladed propellers

5. Family b.69.4.0: automated matches [191412] (1 protein)
   not a true family

6. Protein automated matches [190568] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187559] (94 PDB entries)

8. Domain d6uifa_: 6uif A: [383904]
   automated match to d4gm9b_
   complexed with q8p

Details for d6uifa_

PDB Entry: 6uif, 1.6 Å

PDB Description: discovery of fragment-inspired heterocyclic benzenesulfonmides as inhibitors of the wdr5-myc interaction

PDB Compounds: (A:) WD repeat domain 5

SCOPe Domain Sequences for d6uifa_:

Sequence, based on SEQRES records:

>d6uifa_ b.69.4.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgis
dvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfde
svriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktlid
ddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtgg
kwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklwk
sdc

Sequence, based on observed residues (ATOM records):

>d6uifa_ b.69.4.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgis
dvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfde
svriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktlid
nppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtggkw
ivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklwksd
c

Timeline for d6uifa_:

• d6uifa_ first appeared in SCOPe 2.07