SCOPe 2.08: Domain d6l88a_: 6l88 A:

Lineage for d6l88a_ (6l88 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d6l88a_: 6l88 A: [380401]
   automated match to d2a3ia_
   complexed with e6r

Details for d6l88a_

PDB Entry: 6l88, 3 Å

PDB Description: crystal structure of mineralocorticoid receptor ligand binding domain in complex with esaxerenone

PDB Compounds: (A:) Mineralocorticoid receptor

SCOPe Domain Sequences for d6l88a_:

Sequence, based on SEQRES records:

>d6l88a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
enllstlnrlagkqmiqvvkwakvlpgfknlpledqitliqyswmslssfalswrsykht
nsqflyfapdlvfneekmhqsamyelcqgmhqislqfvrlqltfeeytimkvllllstip
kdglksqaafeemrtnyikelrkmvtkspnnsgqswqrfyqltklldsmhdlvsdllefc
fytfreshalkvefpamlveiisdqlpkvesgnakplyfhr

Sequence, based on observed residues (ATOM records):

>d6l88a_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
enllstlnrlagkqmiqvvkwakvlpgfknlpledqitliqyswmslssfalswrsykht
nsqflyfapdlvmyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaaf
eemrtnyikelrkmvtkspngqswqrfyqltklldsmhdlvsdllefcfypamlveiisd
qlpkvgnakplyfhr

Timeline for d6l88a_:

• d6l88a_ first appeared in SCOPe 2.07