SCOPe 2.07: Domain d6peyc_: 6pey C:

Lineage for d6peyc_ (6pey C:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.23: FAD-linked oxidoreductase [51730] (3 families)
   distinct cofactor-binding mode from both FMN- and NAD(P)-linked TIM-barrel oxidoreductases; families are related by a circular permutation

5. Family c.1.23.1: Methylenetetrahydrofolate reductase [51731] (2 proteins)
   automatically mapped to Pfam PF02219

6. Protein automated matches [193645] (4 species)
   not a true protein

7. Species Escherichia coli [TaxId:562] [374669] (1 PDB entry)

8. Domain d6peyc_: 6pey C: [374671]
   automated match to d2fmna_
   complexed with fad; mutant

Details for d6peyc_

PDB Entry: 6pey, 2.88 Å

PDB Description: mthfr with mutation asp120ala

PDB Compounds: (C:) Methylenetetrahydrofolate reductase

SCOPe Domain Sequences for d6peyc_:

Sequence, based on SEQRES records:

>d6peyc_ c.1.23.1 (C:) automated matches {Escherichia coli [TaxId: 562]}
gqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtygansgerdrthsiikgikdr
tgleaaphltcidatpdelrtiardywnngirhivalrgalppgsgkpemyasdlvtllk
evadfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylrfrdrcvs
agidveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvganiamdm
vkilsregvkdfhfytlnraemsyaichtlgvrp

Sequence, based on observed residues (ATOM records):

>d6peyc_ c.1.23.1 (C:) automated matches {Escherichia coli [TaxId: 562]}
gqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtygansgerdrthsiikgikdr
tgleaaphltcidatpdelrtiardywnngirhivalrgalppgpemyasdlvtllkeva
dfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylrfrdrcvsagi
dveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvganiamdmvki
lsregvkdfhfytlnraemsyaichtlgvrp

Timeline for d6peyc_:

• d6peyc_ is new in SCOPe 2.07-stable
  
• d6peyc_ appears in the current release, SCOPe 2.08