SCOPe 2.07: Domain d6nh4a_: 6nh4 A:

Lineage for d6nh4a_ (6nh4 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187302] (87 PDB entries)

8. Domain d6nh4a_: 6nh4 A: [366316]
   automated match to d3e7sa_
   complexed with btb, cl, gd, gol, h4b, hem, kla, zn

Details for d6nh4a_

PDB Entry: 6nh4, 2.27 Å

PDB Description: structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2r,4s)-4-fluoropyrrolidin-2-yl) ethyl)phenethyl)-4-methylpyridin-2-amine

PDB Compounds: (A:) Endothelial nitric oxide synthase splice variant eNOS13A

SCOPe Domain Sequences for d6nh4a_:

Sequence, based on SEQRES records:

>d6nh4a_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fprvknwevgsitydtlsaqaqqdgpctprrclgslvfprklqgrpspgppapeqllsqa
rdfinqyyssikrsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvgr
iqwgklqvfdardcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwnsq
lvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllpp
elvlevplehptlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrnl
cdphryniledvavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatasf
mkhleneqkarggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d6nh4a_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fprvknwevgsitydtlsaqaqqdgpctprrclgslvfprklapeqllsqardfinqyys
sikrsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvgriqwgklqvf
dardcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwnsqlvryagyrq
qdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllppelvlevple
hptlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrnlcdphrynil
edvavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatasfmkhleneqk
arggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Timeline for d6nh4a_:

• d6nh4a_ is new in SCOPe 2.07-stable
  
• d6nh4a_ appears in the current release, SCOPe 2.08