SCOPe 2.08: Domain d5zwfa_: 5zwf A:

Lineage for d5zwfa_ (5zwf A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [101432] (25 PDB entries)

8. Domain d5zwfa_: 5zwf A: [355062]
   automated match to d1ie9a_
   complexed with 9kr

Details for d5zwfa_

PDB Entry: 5zwf, 2.1 Å

PDB Description: covalent bond formation between histidine of vitamin d receptor (vdr) and a full agonist having a enone with a beta methyl group via conjugate addition reaction

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d5zwfa_:

Sequence, based on SEQRES records:

>d5zwfa_ a.123.1.1 (A:) Vitamin D nuclear receptor {Norway rat (Rattus norvegicus) [TaxId: 10116]}
klseeqqhiiailldahhktydptyadfrdfrppvrmdgstgsvtldlsplsmlphladl
vsysiqkvigfakmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdy
kydvtdvskaghtlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklve
aiqdrlsntlqtyircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmk
ltplvlevfgn

Sequence, based on observed residues (ATOM records):

>d5zwfa_ a.123.1.1 (A:) Vitamin D nuclear receptor {Norway rat (Rattus norvegicus) [TaxId: 10116]}
klseeqqhiiailldahhktydptyadfrdfrppvrlsmlphladlvsysiqkvigfakm
ipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdykydvtdvskaghtl
elieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklveaiqdrlsntlqtyi
rcrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmkltplvlevfgn

Timeline for d5zwfa_:

• d5zwfa_ first appeared in SCOPe 2.07