SCOPe 2.08: Domain d5y8oa2: 5y8o A:160-290

Lineage for d5y8oa2 (5y8o A:160-290)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

4. Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

5. Family a.100.1.0: automated matches [227147] (1 protein)
   not a true family

6. Protein automated matches [226851] (46 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [354674] (11 PDB entries)

8. Domain d5y8oa2: 5y8o A:160-290 [354754]
   Other proteins in same PDB: d5y8oa1, d5y8ob1, d5y8ob3
   automated match to d1yb4a2
   complexed with 3oh, 9on, akr, gol, nad

Details for d5y8oa2

PDB Entry: 5y8o, 2.05 Å

PDB Description: mycobacterium tuberculosis 3-hydroxyisobutyrate dehydrogenase (mthibadh) + nad + 3-hydroxy propionate (3-hp)

PDB Compounds: (A:) Probable 3-hydroxyisobutyrate dehydrogenase

SCOPe Domain Sequences for d5y8oa2:

Sequence; same for both SEQRES and ATOM records:

>d5y8oa2 a.100.1.0 (A:160-290) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
aagagqaakvcnnmvlavqqiaiaeafvlaeklglsaqslfdvitgatgncwavhtncpv
pgpvptspanndfkpgfstalmnkdlglamdavaatgataplgshaadiyakfaadhadl
dfsavihtlra

Timeline for d5y8oa2:

• d5y8oa2 first appeared in SCOPe 2.07