SCOPe 2.07: Domain d5yxza1: 5yxz A:1-169

Lineage for d5yxza1 (5yxz A:1-169)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (80 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (34 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (286 PDB entries)

8. Domain d5yxza1: 5yxz A:1-169 [351339]
   Other proteins in same PDB: d5yxza2
   automated match to d4lyhb_
   complexed with 94c, edo, gdp, mg

Details for d5yxza1

PDB Entry: 5yxz, 1.7 Å

PDB Description: co-crystal structure of kras (g12c) covalently bound with quinazoline based inhibitor jbi484

PDB Compounds: (A:) GTPase KRas

SCOPe Domain Sequences for d5yxza1:

Sequence; same for both SEQRES and ATOM records:

>d5yxza1 c.37.1.8 (A:1-169) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetslldildtag
qeeysamrdqymrtgegfllvfainntksfedihhyreqikrvkdsedvpmvlvgnksdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhkek

Timeline for d5yxza1:

• d5yxza1 is new in SCOPe 2.07-stable
  
• d5yxza1 appears in the current release, SCOPe 2.08