Lineage for d1cw1a_ (1cw1 A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2513202Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2513203Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2513204Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
    the active site is between the two identical subunits
  6. 2513266Protein Isocitrate dehydrogenase, ICDH [53668] (2 species)
  7. 2513270Species Escherichia coli [TaxId:562] [53669] (27 PDB entries)
  8. 2513278Domain d1cw1a_: 1cw1 A: [35069]
    complexed with ict, mn, so4; mutant

Details for d1cw1a_

PDB Entry: 1cw1 (more details), 2.1 Å

PDB Description: crystal structure of isocitrate dehydrogenase mutant k230m bound to isocitrate and mn2+
PDB Compounds: (A:) isocitrate dehydrogenase

SCOPe Domain Sequences for d1cw1a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1cw1a_ c.77.1.1 (A:) Isocitrate dehydrogenase, ICDH {Escherichia coli [TaxId: 562]}
eskvvvpaqgkkitlqngklnvpenpiipyiegdgigvdvtpamlkvvdaavekaykger
kiswmeiytgekstqvygqdvwlpaetldlireyrvaikgplttpvgggirslnvalrqe
ldlyiclrpvryyqgtpspvkhpeltdmvifrensediyagiewkadsadaekvikflre
emgvkkirfpehcgigikpcseegtkrlvraaieyaiandrdsvtlvhmgnimkftegaf
kdwgyqlareefggelidggpwlkvknpntgkeivikdviadaflqqillrpaeydviac
mnlngdyisdalaaqvggigiapganigdecalfeathgtapkyagqdkvnpgsiilsae
mmlrhmgwteaadlivkgmegainaktvtydferlmdgakllkcsefgdaiienm

SCOPe Domain Coordinates for d1cw1a_:

Click to download the PDB-style file with coordinates for d1cw1a_.
(The format of our PDB-style files is described here.)

Timeline for d1cw1a_: