SCOP 1.67: Domain d1dr1__: 1dr1 -

Lineage for d1dr1__ (1dr1 -)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.71: Dihydrofolate reductases [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductases [53597] (1 family)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins)

6. Protein Dihydrofolate reductases, eukaryotic type [53605] (4 species)

7. Species Chicken (Gallus gallus) [TaxId:9031] [53606] (8 PDB entries)

8. Domain d1dr1__: 1dr1 - [34896]
   complexed with bio, ca, nap

Details for d1dr1__

PDB Entry: 1dr1, 2.2 Å

PDB Description: 2.2 angstroms crystal structure of chicken liver dihydrofolate reductase complexed with nadp+ and biopterin

SCOP Domain Sequences for d1dr1__:

Sequence; same for both SEQRES and ATOM records:

>d1dr1__ c.71.1.1 (-) Dihydrofolate reductases, eukaryotic type {Chicken (Gallus gallus)}
vrslnsivavcqnmgigkdgnlpwpplrneykyfqrmtstshvegkqnavimgkktwfsi
peknrplkdrinivlsrelkeapkgahylskslddalalldspelkskvdmvwivggtav
ykaamekpinhrlfvtrilhefesdtffpeidykdfkllteypgvpadiqeedgiqykfe
vyqksv

Timeline for d1dr1__:

• d1dr1__ first appeared (with stable ids) in SCOP 1.55
  
• d1dr1__ appears in SCOP 1.65
  
• d1dr1__ appears in SCOP 1.69
  
• d1dr1__ appears in the current release, SCOPe 2.08, called d1dr1a_