SCOPe 2.08: Domain d1gpla2: 1gpl A:1-336

Lineage for d1gpla2 (1gpl A:1-336)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.19: Pancreatic lipase, N-terminal domain [53577] (2 proteins)
   automatically mapped to Pfam PF00151

6. Protein Pancreatic lipase, N-terminal domain [53578] (6 species)
   contains additional, colipase-binding domain

7. Species Guinea pig (Cavia porcellus) [TaxId:10141] [53582] (1 PDB entry)

8. Domain d1gpla2: 1gpl A:1-336 [34793]
   Other proteins in same PDB: d1gpla1
   complexed with ca

Details for d1gpla2

PDB Entry: 1gpl, 2.01 Å

PDB Description: rp2 lipase

PDB Compounds: (A:) rp2 lipase

SCOPe Domain Sequences for d1gpla2:

Sequence; same for both SEQRES and ATOM records:

>d1gpla2 c.69.1.19 (A:1-336) Pancreatic lipase, N-terminal domain {Guinea pig (Cavia porcellus) [TaxId: 10141]}
aevcyshlgcfsdekpwagtsqrpikslpsdpkkintrfllytnenqnsyqlitatdiat
ikasnfnlnrktrfiihgftdsgenswlsdmcknmfqvekvncicvdwkggskaqysqas
qnirvvgaevaylvqvlstslnyapenvhiighslgahtageagkrlnglvgritgldpa
epyfqdtpeevrldpsdakfvdvihtdispilpslgfgmsqkvghmdffpnggkdmpgck
tgiscnhhrsieyyhssilnpegflgypcasydefqesgcfpcpakgcpkmghfadqypg
ktnaveqtfflntgasdnft

Timeline for d1gpla2:

• d1gpla2 first appeared (with stable ids) in SCOP 1.55, called d1gpl_2
  
• d1gpla2 appears in SCOPe 2.07