Lineage for Family c.52.1.36: Splicing factor Prp8 endonuclease-like domain

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies) core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.36: Splicing factor Prp8 endonuclease-like domain [345968] (1 protein) Pfam PF10596 Likely homology to endonuclease domains discussed in PubMed 21441348, PubMed 23354046