Lineage for d1dibb2 (1dib B:1002-1126)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2127441Fold c.58: Aminoacid dehydrogenase-like, N-terminal domain [53222] (1 superfamily)
    core: 3 layers: a/b/a; parallel beta-sheet of 4 strands; 2134
  4. 2127442Superfamily c.58.1: Aminoacid dehydrogenase-like, N-terminal domain [53223] (6 families) (S)
  5. 2127608Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase [53235] (1 protein)
    automatically mapped to Pfam PF00763
  6. 2127609Protein Tetrahydrofolate dehydrogenase/cyclohydrolase [53236] (3 species)
    the two-domain organization is similar to that of aminoacid dehydrogenases, but both domains are truncated
  7. 2127615Species Human (Homo sapiens) [TaxId:9606] [53237] (4 PDB entries)
  8. 2127623Domain d1dibb2: 1dib B:1002-1126 [33933]
    Other proteins in same PDB: d1diba1, d1dibb1
    complexed with l34, nap

Details for d1dibb2

PDB Entry: 1dib (more details), 2.7 Å

PDB Description: human methylenetetrahydrofolate dehydrogenase / cyclohydrolase complexed with nadp and inhibitor ly345899
PDB Compounds: (B:) methylenetetrahydrofolate dehydrogenase/cyclohydrolase

SCOPe Domain Sequences for d1dibb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1dibb2 c.58.1.2 (B:1002-1126) Tetrahydrofolate dehydrogenase/cyclohydrolase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1dibb2:

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Timeline for d1dibb2:

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